327971-24-4Relevant academic research and scientific papers
Synthesis and antioxidant activities of acetamidomethylsulfonyl bis heterocycles-oxazolyl/thiazolyl/imidazolyl-1,3,4-Oxadiazoles
Mahaboob Basha, Nabhubygari,Lavanya, Gopala,Padmaja, Adivireddy,Padmavathi, Venkatapuram
, p. 511 - 520 (2013)
A new class of acetamidomethylsulfonyl bis heterocycles-oxazolyl-1,3,4- oxadiazoles, -thiazolyl-1,3,4-oxadiazoles, and -imidazolyl-1,3,4-oxadiazoles were synthesized from the synthetic intermediates, methyl 2-((4-aryloxazol-2- ylcarbamoyl)methylsulfonyl)acetate, methyl 2-((4-arylthiazol-2-ylcarbamoyl) methylsulfonyl)acetate, and methyl 2-((4-aryl-1H-imidazol-2-ylcarbamoyl) methylsulfonyl)acetate. All the title compounds were tested for their antioxidant activity. The oxadiazolylmethylsulfonyloxazolylacetamide displayed excellent radical-scavenging activity when compared with the standard ascorbic acid. A new class of acetamidomethylsulfonyl bis heterocycles-oxazolyl/ thiazolyl/imidazolyl-1,3,4-oxadiazoles were synthesized and tested for their antioxidant activity. The oxadiazolylmethylsulfonyloxazolylacetamide displayed excellent radical-scavenging activity when compared with the standard ascorbic acid.
