328084-40-8Relevant academic research and scientific papers
Rapid Chemical Synthesis of Self-Assembling Semi-Synthetic Proteins
Bhandari, Pavankumar Janardhan,Rao, Kasuladevu Jegannadha,Reddy, Mullapudi Mohan,Sandanaraj, Britto S.
, p. 8576 - 8589 (2021/07/19)
The design of well-defined monodispersed self-assembling semi-synthetic proteins is emerging as a promising research avenue. These proteins hold great potential to be used as scaffolds for various protein nanotechnology applications. Currently, there are very few chemical methods reported; however, they suffer from elaborate multistep organic synthesis. Herein, we report a new chemical methodology for the rapid synthesis of a diverse set of semi-synthetic protein families, which include protein amphiphiles, facially amphiphilic protein-dendron conjugates, and pH-sensitive protein-dendron conjugates. This chemical method holds great potential to access a wide variety of semi-synthetic proteins in a short time.
Fluorophore-cored dendrimers for patterns in metalloprotein sensing
Jiwpanich, Siriporn,Sandanaraj, Britto S.,Thayumanavan
supporting information; experimental part, p. 806 - 808 (2009/07/10)
In fluorophore-cored dendrimers with peripheral binding functionalities, the effect of generation upon protein binding-induced fluorescence quenching can be unpredictable; this is because the increase in fluorophore-binding functionality distance with gen
