32849-41-5

Upstream product

• 90-15-3 α-naphthol 
• 74-88-4 methyl iodide 
• 72839-13-5 1-(2,6-dimethylphenyl)-2-propyn-1-one 

Downstream Products

• 37014-88-3 4-phenyl-7-methyl-1,2,3,4-tetrahydronaphth-1-one 
• 204583-83-5 (S)-Methoxy-phenyl-acetic acid (S)-(8-{8-[(S)-((S)-2-methoxy-2-phenyl-acetoxy)-phenyl-methyl]-naphthalen-1-yloxy}-naphthalen-1-yl)-phenyl-methyl ester 

Relevant academic research and scientific papers

The Gas-Flow Thermolysis of 1-Isobutenyl Alkynyl and 2-Methylphenyl Alkynyl Ketones. Synthesis of Methylenomycin B

The gas-flow thermolysis of 1-isobutenyl alkynyl or 2-methyphenyl alkynyl ketones were found to lead to phenols and cyclopentenones or to naphthols and indanones, respectively.These conversions involve two cyclization processes so far unknown with α-alkynones; they are interpreted as intramolecular additions of an allylic or a benzylic C,H bond to a triple bond which may occur in two directions.In addition, the cyclopentenones formed by the α-alkynone cyclization, a known carbene process yielding 5-rings, were also found.The available evidence ruled out a carbene process yielding 6-rings.The addition process yielding 5-rings was applied to a short (but low yield) synthesis of methylenomycin B.