32849-90-4Relevant academic research and scientific papers
Highly efficient one-pot four-component Kabachnik-Fields synthesis of novel α-amino phosphonates under solvent-free and catalyst-free conditions
Rashid, Zahra,Naeimi, Hossein,Ghahremanzadeh, Ramin
, p. 99148 - 99152 (2015)
In the present study, a simple and highly efficient protocol for the preparation of novel α-amino phosphonates is achieved based on the one-pot reaction of ninhydrin, 1,2-phenylenediamines, aniline derivatives, and dialkyl or diaryl phosphites, without using any catalyst under solvent-free conditions. The main advantages of the reaction are short reaction time, high yields, simple workup, and no need for further purification.
