328533-94-4Relevant academic research and scientific papers
Tf2O-Promoted Intramolecular Schmidt Reaction of the ω-Azido Carboxylic Acids
Wang, Xue-Juan,Su, Yan,Li, Rui,Gu, Peiming
, p. 5816 - 5824 (2018/05/14)
A designed Tf2O-promoted intramolecular Schmidt reaction of 2-substituted ω-azido carboxylic acids was demonstrated. Tf2O was used as an activation reagent for the carboxylic acid, and ω-azido anhydride was in situ generated, releasing a molecular TfOH, which acted as an acid promoter for the Schmidt process. A series of 2-substituted pyrrolidines was produced and acetylated for better purification. The strategy was also efficient for conversion of a 4-substituted ω-azido carboxylic acid to the tricyclic lactam.
Method of manufacturing ketones
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, (2008/06/13)
The invention relates to a method for the manufacture of ketones which comprises oxidizing an n-olefin in the presence of a catalyst containing palladium, copper, a halogen, and at least one of specific tertiary amines.
