32858-99-4

Basic information

• Product Name: 4’-bromo-3-nitrobiphenyl
• Synonyms: 4’-bromo-3-nitrobiphenyl
• CAS NO: 32858-99-4
• Molecular Weight: 278.105
• Mol File: 32858-99-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4’-bromo-3-nitrobiphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 4’-bromo-3-nitrobiphenyl(32858-99-4)
• EPA Substance Registry System: 4’-bromo-3-nitrobiphenyl(32858-99-4)

Safety Data

• Hazardous Substances Data: 32858-99-4(Hazardous Substances Data)

Upstream product

• 673-40-5 4-bromobenzenediazonium tetrafluoroborate 
• 98-95-3 nitrobenzene 

Downstream Products

• 40641-71-2 4'-bromo-[1,1'-biphenyl]-3-amine 

Relevant articles and documents

Copper catalysed Gomberg-Bachmann-Hey reactions of arenediazonium tetrafluoroborates and heteroarenediazonium o-benzenedisulfonimides. Synthetic and mechanistic aspects

Gomberg-Bachmann-Hey reactions were carried out in the presence of copper as a catalyst and gave rise to biaryls or heterobiaryls in good yields and in mild reaction conditions. A computational study of some key points of the reaction was performed. The results are coherent with the experimental data and confirm some aspects of the mechanism. The reaction free energies for the reduction in benzene by CuI of a set of 40 (hetero)arenediazonium tetrafluoroborates were calculated. Both the experiments and the calculations showed that in the coupling with substituted solvents (toluene, bromobenzene, nitrobenzene and anisole) the binding to the ortho position was always favoured.