32864-29-2

Basic information

• Product Name: 2-BROMO-3-PHENYLPYRIDINE
• Synonyms: 2-BROMO-3-PHENYLPYRIDINE
• CAS NO: 32864-29-2
• Molecular Formula: C₁₁H₈BrN
• Molecular Weight: 234.09
• Mol File: 32864-29-2.mol

Chemical Properties

• Boiling Point: 321.3 ºC at 760 mmHg
• Flash Point: 148.1 ºC
• Appearance: /
• Density: 1.426 g/cm³
• Vapor Pressure: 0.000563mmHg at 25°C
• Refractive Index: 1.606
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 0.41±0.10(Predicted)
• CAS DataBase Reference: 2-BROMO-3-PHENYLPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-3-PHENYLPYRIDINE(32864-29-2)
• EPA Substance Registry System: 2-BROMO-3-PHENYLPYRIDINE(32864-29-2)

Safety Data

• Hazardous Substances Data: 32864-29-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Bromo-3-phenylpyridine is used as a chemical intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs with improved therapeutic properties. Its unique structure allows for the creation of diverse drug candidates with potential applications in treating a range of medical conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Bromo-3-phenylpyridine serves as a key intermediate in the production of various agrochemicals, including pesticides and herbicides. Its incorporation into these compounds can enhance their effectiveness in controlling pests and weeds, thereby improving crop yields and food security.
Used in Academic Research:
2-Bromo-3-phenylpyridine is employed as a building block in organic chemistry for conducting various organic reactions. Researchers utilize its unique structure to explore new synthetic pathways, develop innovative methodologies, and gain insights into reaction mechanisms, ultimately contributing to the advancement of organic chemistry and related fields.

InChI:InChI=1/C11H8BrN/c12-11-10(7-4-8-13-11)9-5-2-1-3-6-9/h1-8H

Upstream product

• 109-04-6 2-bromo-pyridine 
• 591-50-4 iodobenzene 
• 103863-15-6 3-phenylpyridine-2-carboxylic acid 
• 35905-85-2 2-bromonicotinic acid 
• 71-43-2 benzene 

Downstream Products

• 103863-15-6 3-phenylpyridine-2-carboxylic acid 
• 57955-12-1 indeno[2,1-b]pyridin-9-one 

Relevant articles and documents

Transition-metal-free decarboxylative halogenation of 2-picolinic acids with dihalomethane under oxygen conditions

A convenient and efficient method for the synthesis of 2-halogen-substituted pyridines is described. The decarboxylative halogenation of 2-picolinic acids with dihalomethane proceeded smoothly via N-chlorocarbene intermediates to afford 2-halogen-substituted pyridines in satisfactory to excellent yields under transition-metal-free conditions. This new type of decarboxylative halogenation is operationally simple and exhibits high functional-group tolerance.

Mild, visible light-mediated decarboxylation of aryl carboxylic acids to access aryl radicals

Herein we present the first example of aryl radical formation via the visible light-mediated decarboxylation of aryl carboxylic acids using photoredox catalysis. This method constitutes a mild protocol for the decarboxylation of cheap and abundant aryl carboxylic acids and tolerates both electron-rich substrates and those lacking ortho-substitution. The in situ formation of an acyl hypobromite is proposed to prevent unproductive hydrogen atom abstraction and trapping of the intermediate aroyloxy radical, enabling mild decarboxylation.

Organometallic compound and organic light emitting device including the same

Disclosed are an organometallic compound and an organic light emitting device comprising the same. The organometallic compound is represented by chemical formula 1. The organic light emitting device using the organometallic compound can have a low driving

Directed deprotonation-transmetalation as a route to substituted pyridines

matrix presented Regioselective C-4 deprotonation of 3-bromopyridine, followed by Li/Zn transmetalation and Pd-mediated coupling processes, provides a flexible entry to 4-substituted and 3,4-disubstituted pyridines. Application of a similar sequence to 2-