328933-49-9

Upstream product

• 328933-48-8 2,2-dimethyl-propionic acid 4-(5-benzyloxy-3-methyl-1H-indol-2yl)-phenyl ester 
• 206550-68-7 1-[2-(4-Chloromethyl-phenoxy)-ethyl]-piperidine 

Downstream Products

• 328933-51-3 2,2-Dimethyl-propionic Acid 4-{5-hydroxy-3-methyl-1-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-1H-indol-2-yl}-phenyl Ester 
• 328933-57-9 4-{5-benzyloxy-3-methyl-1-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-1H-indol-2-yl}-phenol 

Relevant academic research and scientific papers

GLUCOPYRANOSIDES CONJUGATES OF 2-(4-HYDROXY-PHENYL)-1- 4-(2-AMIN-1-YL-ETHOXY)-BENZYL]-1H-INDOL-5-OLS

This invention provides tissue selective estrogens of formula (I) having structure (I) wherein: R1 and R2 are independently, hydrogen, alkyl chain of 1-6 carbon atoms, benzyl, acyl of 2-7 carbon atoms, benzoyl, (1) or (2); X is hydrogen, alkyl of 1-6 carbon atoms, CN, halogen, trifuoromethyl, or thioalkyl of 1-6 carbon atoms; n = 1-3; with the proviso that at least one of R1 or R2 is (1) or (2); or a pharmaceutically acceptable salt thereof.

Glucopyranosides conjugates of 2-(4-hydroxy-phenyl)-3-methyl-1-[4-(2-amin-1-yl-ethoxy)-benzyl]-1H-indol-5-ols

This invention provides tissue selective estrogens of formula I having the structure wherein: R1and R2are independently, hydrogen, alkyl chain of 1-6 carbon atoms, benzyl, acyl of 2-7 carbon atoms, benzoyl, X is hydrogen, alkyl of 1-6 carbon atoms, CN, halogen, trifluoromethyl, or thioalkyl of 1-6 carbon atoms; n=1-3; with the proviso that at least one of R1or R2are not hydrogen, alkyl chain of 1-6 carbon atoms, benzyl, acyl of 2-7 carbon atoms, or benzoyl; or a pharmaceutically acceptable salt thereof.