328947-81-5

Usage

Chemical Structure

Quinolinone structure modified with a dimethylamino and trifluoromethyl group

Fluorinated Derivative

Contains fluorine atoms

Potential Pharmaceutical Applications

Studied in neuroscience and neuropharmacology

Fluorescent Probe

Investigated for cellular imaging

Drug Candidate

Potential targeting neurotransmitter receptors

Unique Structure

Functional groups offer versatility in pharmaceutical research and development

Upstream product

• 328955-57-3 6-amino-4-(trifluoromethyl)quinoline-2-(1H)-one 
• 50-00-0 formaldehyd 

Relevant academic research and scientific papers

Discovery of 6-N,N-Bis(2,2,2-trifluoroethyl)amino-4- trifluoromethylquinolin-2(1H)-one as a novel selective androgen receptor modulator

The androgen receptor is a member of the extended family of nuclear receptors and is widely distributed throughout the body. Androgen therapy is used to compensate for low levels of the natural hormones testosterone (T) and dihydrotestosterone and consist

Bicyclic androgen and progesterone receptor modulator compounds and methods

The present invention is directed to compounds, pharmaceutical compositions, and methods for modulating processes mediated by AR and PR. More particularly, the invention relates to nonsteroidal compounds and compositions that are high affinity, high specificity agonists, partial agonists (i.e., partial activators and/or tissue-specific activators) and antagonists for AR and PR. Also provided are methods of making such compounds and pharmaceutical compositions, as well as critical intermediates used in their synthesis.