328974-69-2

Upstream product

• 210345-07-6 5R-vinyl proline methyl ester 
• 138958-09-5 cis-N-(methoxycarbonyl)-5-<2-(trimethylsilyl)ethynyl>-L-proline methyl ester 
• 185385-13-1 1-carbomethoxy-5-methoxy-L-proline methyl ester 
• 328974-68-1 N-[(2R)-t-butoxycarbonylamino-(3R)-phenyl-4-pentenoyl]-(5R)-vinylproline methyl ester 

Downstream Products

• 328974-88-5 (3S,4S,7R,10S)-1-aza-3-pyroglutamoylamino-4-phenyl-10-carbomethoxybicyclo[5.3.0]decane 
• 328974-71-6 (3S,4S,7R,10S)-1-aza-3-t-butoxycarbonylamino-4-phenyl-10-carbomethoxybicyclo[5.3.0]decane 

Relevant academic research and scientific papers

Anodic amide oxidation/olefin metathesis strategies: Developing a unified approach to the synthesis of bicyclic lactam peptidomimetics

In connection with efforts to build constrained peptidomimetics for the endocrine hormone TRH, a general strategy for the construction of bicyclic lactam peptide building blocks has been developed. This strategy used an anodic amide oxidation to selective