329026-37-1

Basic information

• Product Name: 1,2-Benzenedicarbonitrile, 3,6-bis(phenylthio)-
• CAS NO: 329026-37-1
• Molecular Formula: C20H12N2S2
• Molecular Weight: 344.461
• Mol File: 329026-37-1.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1,2-Benzenedicarbonitrile, 3,6-bis(phenylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Benzenedicarbonitrile, 3,6-bis(phenylthio)-(329026-37-1)
• EPA Substance Registry System: 1,2-Benzenedicarbonitrile, 3,6-bis(phenylthio)-(329026-37-1)

Safety Data

• Hazardous Substances Data: 329026-37-1(Hazardous Substances Data)

Upstream product

• 4733-50-0 2,3-dicyano-1,4-hydroquinone 
• 108-98-5 thiophenol 
• 344453-20-9 2,3-dicyano-1,4-phenylene bis(trifluoromethanesulfonate) 
• 667938-12-7 3,6-bis(4’-methylphenylsulfonyloxy)phthalonitrile 

Downstream Products

• 918779-67-6 3,6-bis[(4-methoxyphenyl)thio]phthalonitrile 
• 773847-99-7 1,4,8,11,15,18,22,25-octakis(phenylsulfanyl)phthalocyanine 

Relevant articles and documents

Breaching the wall: morphological control of efficacy of phthalocyanine-based photoantimicrobials

An efficient treatment of infections using antimicrobial photodynamic therapy (aPDT) anticipates that uptake of photosensitizer (PS) by bacterial cells is very fast and effective. In this work, the design, synthesis, characterization, and photodynamic activity of amphiphilic, water-soluble zinc(ii)phthalocyanine (Zn(ii)Pc) molecules bearing none, three or six thiophenyl moieties are described. We show that PSs that contain no or flexible substituents on non-peripheral positions can photoinactivate microbes at very low loading concentrations and low light doses. In contrast, a PS derivative that contains non-flexible substituents is rendered less effective, despite an increased generation of cytotoxic singlet oxygen, higher lipophilicity and a lower tendency to aggregate. Our unexpected finding emphasizes the role of the morphology of PSs in bacterial cell-molecule interactions and suggests another relevant and hitherto disregarded characteristic to improve PS design.

The effect of substitutents at alkylsulfanyl/arylsulfanyl non-peripherally substituted phthalocyanines: Spectral and photophysical properties, basicity and photostability

A series of magnesium, zinc and metal-free derivatives of non-peripherally substituted phthalocyanines (Pcs) bearing alkylsulfanyl or arylsulfanyl groups of different bulkiness was synthesized. Their spectral and photophysical properties including also th

Routes to some 3,6-disubstituted phthalonitriles and examples of phthalocyanines derived therefrom. An overview

The paper reviews a selection of synthetic pathways that provide access to 3,6-disubstituted phthalonitriles, precursors for the synthesis of 1,4,8,11,15,18,22,25-octasubstituted phthalocyanine derivatives. Early routes using Diels-Alder reactions for the