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Usage

Uses

Used in Pharmaceutical Industry:
N-[3-(1H-Benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide is used as a bioactive molecule for the development of new drugs targeting specific biological pathways. Its unique structure allows it to interact with cellular targets, making it a promising candidate for the treatment of various diseases.
Used in Chemical Research:
In the field of chemical research, N-[3-(1H-Benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide serves as a key intermediate in the synthesis of more complex molecules with potential applications in material science, pharmaceuticals, and other industries.
Used in Hedgehog Signaling Inhibition:
N-[3-(1H-Benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide, specifically as SANT-2, is used as an inhibitor of the Smoothened (Smo) protein, which is a key component of the Hedgehog signaling pathway. This application is particularly relevant in the study and treatment of certain types of cancers, as the Hedgehog pathway is known to play a role in tumor growth and progression.
Used in Drug Delivery Systems:
Similar to gallotannin, N-[3-(1H-Benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide may also be utilized in drug delivery systems to improve its bioavailability and therapeutic efficacy. By employing various carriers such as organic and metallic nanoparticles, the compound can be more effectively delivered to target cells, enhancing its potential as a therapeutic agent.

Biochem/physiol Actions

SANT-2 is a potent sonic hedgehog pathway (shh) antagonist that directly inhibits by binding to the smoothened receptor.