329221-38-7

Basic information

• Product Name: AX 20017
• Synonyms: AX 20017;PknG Inhibitor;2-(cyclopropanecarboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide
• CAS NO: 329221-38-7
• Molecular Formula: C13H16N2O2S
• Molecular Weight: 264.34334
• Mol File: 329221-38-7.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: AX 20017(CAS DataBase Reference)
• NIST Chemistry Reference: AX 20017(329221-38-7)
• EPA Substance Registry System: AX 20017(329221-38-7)

Safety Data

• Hazardous Substances Data: 329221-38-7(Hazardous Substances Data)

Usage

Uses

AX 20017 is a highly selective PknG Inhibitor, blocking the proliferation of M. tuberculosis.

Upstream product

• 4023-34-1 cyclopropanecarboxylic acid chloride 
• 4815-28-5 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide 
• 108-94-1 cyclohexanone 

Relevant articles and documents

New method for the synthesis of 2-acylamino-1-benzothiophene-3-carboxamide derivatives from the corresponding esters

An unusual chemical method has been applied for the preparation of 1-benzothiophene-3-carboxamide derivatives from esters by reaction with lithium amide in tetrahydrofurane. Copyright Taylor & Francis Group, LLC.

Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3

A series of 2-acylaminothiophene-3-carboxamides has been identified which exhibit potent inhibitory activity against the FLT3 tyrosine kinase. Compound 44 inhibits the isolated enzyme (IC50 = 0.027 μM) and blocks the proliferation of MV4-11 cel