329235-22-5

Upstream product

• 89-95-2 2-methyl-benzyl alcohol 
• 1694-92-4 2-Nitrobenzenesulfonyl chloride 
• 90-02-8 salicylaldehyde 

Downstream Products

• 22293-32-9 (2-hydroxyphenyl)(2-nitrophenyl)methanone 
• 908073-40-5 MAL₂-61 
• 1402084-10-9 (Z)-2'-(2-nitrobenzenesulfonyloxy)-5-benzylidenethiazolidine-2,4-dione 

Relevant academic research and scientific papers

Synthesis and antiproliferative evaluation of 2'-arenesulfonyloxy-5- benzylidene-thiazolidine-2,4-diones

A series of 2'-arenesulfonyloxy-5-benzylidene-thiazolidine-2,4-diones (TZDs) were synthesized and examined for their antiproliferative effects on a panel of carcinoma cell lines. Our results indicated that initial synthesis of 5-[2'-hydroxybenzylidene]-2,

Design and synthesis of novel N-benzylidenesulfonohydrazide inhibitors of murC and murD as potential antibacterial agents

A series of novel N-benzylidenesulfonohydrazide compounds were designed and synthesized as inhibitors of UDP-N-acetylmuramic acid:L-alanine ligase (MurC) and UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (MurD) from E. coli, involved in the biosynthes

New arylsulfonohydrazide inhibitors of enzymes MurC and MurD

This invention belongs to the field of pharmaceutical chemistry and relates to new arylsulfonohydrazides as inhibitors of UDP-N-acetylmuramyl:L-alanine ligaze (MurC) and UDP-N-acetylmuramyl-L-alanine:D-glutamate ligaze (MurD), to procedures for their preparation and pharmaceutical preparations containing the same. The enzymes MurC and MurD are the key enzymes involved in the synthesis of bacterial peptidoglycan, so arylsulfonohydrazide inhibitors possess antibacterial activity. Compounds of general formula I and the pharmaceutically acceptable salts are described. The appropriate substituents are clearly presented in the body of the text and in claims.

A concise approach to the preparation of 2-hydroxydiarylketones by an intramolecular acyl radical ipso substitution

Substituted 2-hydroxydiarylketones have been simply prepared using an intramolecular acyl radical [1,6] ipso substitution reaction. (C) 2000 Elsevier Science Ltd.