329309-03-7Relevant academic research and scientific papers
An efficient conversion of the carboxylic group of N-Fmoc α-amino acids/peptide acids into N-formamides employing isocyanates as key intermediates
Sudarshan,Narendra,Hemantha,Sureshbabu, Vommina V.
, p. 9804 - 9807 (2008/03/27)
(Chemical Equation Presented) Reaction of 96% formic acid with isocyanates derived from N-Fmoc α-amino acids/peptide acids catalyzed by DMAP has yielded a new class of stable formamides as crystalline solids which have been characterized by IR, 1/su
Fmoc-amino acid azides in peptide synthesis
Vasanthakumar, Ganga-Ramu,Ananda, Kuppanna,Suresh Babu, Vommina V
, p. 1733 - 1735 (2007/10/03)
Fmoc-amino acid azides can be prepared from the corresponding acid chlorides and sodium azide. All the compounds made have been obtained as solids in good yield and purity. They are found to be shelf stable at room temperature for longer periods. Their storage at room temperature does not lead to the formation of isocyanates. Employing them as coupling agents, the synthesis of a few dipeptides is described.
(Fluoren-9-ylmethoxy)carbonyl (Fmoc) amino acid azides: Synthesis, isolation, characterisation, stability and application to synthesis of peptides
Babu, Vommina V. Suresh,Ananda, Kuppanna,Vasanthakumar, Ganga-Ramu
, p. 4328 - 4331 (2007/10/03)
The synthesis of Fmoc amino acid azides starting from the corresponding protected amino acid and sodium azide (NaN3) by the mixed anhydride method using isobutoxycarbonyl chloride (IBC-Cl) or by the acid chloride method is described. Isolated as crystalli
