329317-41-1

Basic information

• Product Name: 4-[3-(2-nitro-4-trifluoromethanesulfonyl-phenoxy)-phenoxy]-benzoic acid
• Synonyms: 4-[3-(2-nitro-4-trifluoromethanesulfonyl-phenoxy)-phenoxy]-benzoic acid
• CAS NO: 329317-41-1
• Molecular Weight: 483.378
• Mol File: 329317-41-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[3-(2-nitro-4-trifluoromethanesulfonyl-phenoxy)-phenoxy]-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[3-(2-nitro-4-trifluoromethanesulfonyl-phenoxy)-phenoxy]-benzoic acid(329317-41-1)
• EPA Substance Registry System: 4-[3-(2-nitro-4-trifluoromethanesulfonyl-phenoxy)-phenoxy]-benzoic acid(329317-41-1)

Safety Data

• Hazardous Substances Data: 329317-41-1(Hazardous Substances Data)

Upstream product

• 1550-27-2 1-chloro-2-nitro-4-[(trifluoromethyl)sulfonyl]benzene 
• 56183-35-8 4-(3-hydroxyphenoxy)benzonic acid 

Relevant articles and documents

Phosphate mimics and methods of treatment using phosphatase inhibitors

The invention relates to trifluoromethyl sulfonyl and trifluoromethyl sulfonamido compounds and the physiologically acceptable salts and the prodrugs thereof. These compounds are expected to modulate the activity of protein tyrosine enzymes which are related to cellular signal transduction, in particular, protein tyrosine phosphatase, and therefore are expected to be useful in the prevention and treatment of disorders associated with abnormal protein tyrosine enzyme related cellular signal transduction such as cancer, diabetes, immuno-modulation, neurologic degenerative diseases, osteoporosis and infectious diseases. The invention also relates to the use of compounds containing fluoromethyl sulfonyl groups as phosphate mimics. These mimics may be used to inhibit, regulate or modulate the activity of a phosphate binding protein in a cell.