329322-38-5

Basic information

• Product Name: (S)-(cyano)(p-bromophenyl)methyl 12β-deoxoartemisinyl ether
• Synonyms: (S)-(cyano)(p-bromophenyl)methyl 12β-deoxoartemisinyl ether
• CAS NO: 329322-38-5
• Molecular Weight: 478.383
• Mol File: 329322-38-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-(cyano)(p-bromophenyl)methyl 12β-deoxoartemisinyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(cyano)(p-bromophenyl)methyl 12β-deoxoartemisinyl ether(329322-38-5)
• EPA Substance Registry System: (S)-(cyano)(p-bromophenyl)methyl 12β-deoxoartemisinyl ether(329322-38-5)

Safety Data

• Hazardous Substances Data: 329322-38-5(Hazardous Substances Data)

Upstream product

• 1122-91-4 4-bromo-benzaldehyde 
• 58289-69-3 2-(4-bromophenyl)-2-hydroxyacetonitrile 
• 71939-50-9 dihydroartemisinin 

Relevant articles and documents

Synthesis and cytotoxicity of dihydroartemisinin ethers containing cyanoarylmethyl group

A new type of ether of dihydroartemisinin containing cyano and aryl groups was prepared and tested for cytotoxicity to A549, P388, L1210 and HT29 cells using the MTT assay. 12k and 12l were the most cytotoxic compounds. 13 lacking the peroxy group showed a 1000-fold less potency than 12l. Similarly, the inactive compound 14 indicated that the position of cyano groups was also important. Flow cytometry data showed that the compounds caused an accumulation of P388 cells in the G1-phase of the cell cycle.