329353-55-1Relevant academic research and scientific papers
Titanium-mediated diastereoselective formation of (Z)-1-(1-alkenyl)-2-substituted-cyclopropyl esters efficient precursors of (Z)- 2,3-methanoamino acids
Racouchot,Ollivier,Salaun
, p. 1729 - 1732 (2007/10/03)
The titanium-mediated cyclopropanation of homoallyl alk-2-enoates, emerged as the most convenient method to form diastereomerically pure (Z)-1-(1-alkenyl)-2-alkylcyclopropanols, precursors of significant 1,1-dimethyleneallylmetal species. Then, azidation of such complexes followed by a simple reduction-oxidation sequence provided diastereochemically pure (Z)-2,3-methanoamino acids.
