329363-45-3

Upstream product

• 299917-90-1 (3aR,8aR)-6-chloro-2,2-dimethyl-4,4,8,8-tetraphenyltetrahydro[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepine 
• 93379-48-7 (R,R)-TADDOL 
• 4735-49-3 1-[(E)-2-nitroethenyl]naphthalene 
• 329363-38-4 (3aR,8aR)-2,2-dimethyl-4,4,8,8-tetraphenylperhydro-6λ⁵-[1,3]dioxolo-[4,5-e][1,3,2]dioxaphosphepin-6-one 

Relevant academic research and scientific papers

Asymmetric Michael additions of a chiral phosphite to nitroalkenes and knoevenagel acceptors

The diastereoselective Michael addition of an enantiopure phosphite to nitroalkenes and α,β-unsaturated malonates is described. High asymmetric inductions were obtained using a readily available TADDOL auxiliary. Racemization-free cleavage of the auxiliar

Asymmetric synthesis of α-substituted β-nitrophosphonic acids by phospha-analogous Michael addition to aromatic nitroalkenes

Asymmetric C-P bond formation through phospha-analogous Michael addition to nitroalkenes leads with high asymmetric induction to α-substituted β-nitrophosphonic acids [Eq.(1)], which constitute valuable bifunctional synthetic building blocks and direct pr