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32949-81-8

α-Ethyl-3-phenoxybenzeneacetic acid, also known as fenfluramine, is a synthetic chemical compound belonging to the phenethylamine class. It was initially developed as a stimulant and anorectic drug, primarily used for the short-term treatment of obesity. Fenfluramine works by releasing serotonin from neurons, which in turn suppresses appetite and increases the feeling of fullness. However, due to its association with serious side effects, including pulmonary hypertension and heart valve damage, its use has been discontinued in many countries. The chemical structure of fenfluramine consists of a phenethylamine core with a phenyl ring at the alpha position, an ethyl group at the beta position, and a phenoxybenzeneacetic acid group attached to the phenyl ring.

32949-81-8

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32949-81-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 32949-81-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,9,4 and 9 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 32949-81:
(7*3)+(6*2)+(5*9)+(4*4)+(3*9)+(2*8)+(1*1)=138
138 % 10 = 8
So 32949-81-8 is a valid CAS Registry Number.

32949-81-8Relevant articles and documents

Unexpected formation of 3,3a,4,7a-tetrahydrobenzofuran-2,5-dione as well as arene carboxylic acids upon formal double exo nucleophilic addition of R1R2C-COO- to anisolechromium tricarbonyl complexes

Bellassoued, Moncef,Chelain, Evelyne,Collot, Jerome,Rudler, Henri,Vaissermann, Jacqueline

, p. 187 - 188 (2007/10/03)

Bis(trimethylsily)ketene acetals of the general structure 2 (R1 = H,Me,R2 = Me,Et,Pr(i),CMe = CH2) react at -78°C in the presence of Bu(t)OK with a series of arenechromium tricarbonyl complexes 3 to give as expected, after oxidation with I2 followed by silica gel chromatography, arylcarboxylic acids 7. In the case of anisolechromium tricarbonyl 8, besides the m-methoxyarylcarboxylic acids, tetrahydrobenzofuran-2,5-diones 11, are formed as the result of a double nucleophilic addition.

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