329686-57-9

Basic information

• Product Name: N^α[(o-Methoxycarbonyl)benzoyl]-(S)-isoleucinamide
• Synonyms: N^α[(o-Methoxycarbonyl)benzoyl]-(S)-isoleucinamide
• CAS NO: 329686-57-9
• Molecular Weight: 292.335
• Mol File: 329686-57-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N^α[(o-Methoxycarbonyl)benzoyl]-(S)-isoleucinamide(CAS DataBase Reference)
• NIST Chemistry Reference: N^α[(o-Methoxycarbonyl)benzoyl]-(S)-isoleucinamide(329686-57-9)
• EPA Substance Registry System: N^α[(o-Methoxycarbonyl)benzoyl]-(S)-isoleucinamide(329686-57-9)

Safety Data

• Hazardous Substances Data: 329686-57-9(Hazardous Substances Data)

Upstream product

• 4376-18-5 Monomethyl phthalate 
• 10466-56-5 L-isoleucine amide hydrochloride 

Relevant articles and documents

Rapid procedure for N-phthaloylation of α-amino carboxamides, α-amino alcohols, α-amino esters and dipeptide derivatives

A rapid, one-pot synthesis and mild procedure for the N-phthaloylation of α-amino carboxamides is described. In acetonitrile, these derivatives react with mono-methylphthalate in the presence of BOP and i-Pr2NEt to afford the intermediate Nα-[(o-methoxycarbonyl)benzoyl]amino carboxamides, which undergo rapid cyclization in the presence of aqueous sodium carbonate to afford the corresponding Nα-phthaloylamino carboxamides in excellent yields. The reaction also works efficiently with α-amino esters, α-amino alcohols and dipeptide esters or amides.