329712-50-7Relevant articles and documents
Synthesis of 1-(2,4-dichlorophenyl)-4-cyano-5-(4-[11C] methoxyphenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide ([ 11C]JHU75528) and 1-(2-bromophenyl)-4-cyano-5-(4-[ 11C]methoxyphenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-c
Fan, Hong,Ravert, Hayden T.,Holt, Daniel P.,Dannals, Robert F.,Horti, Andrew G.
, p. 1021 - 1036 (2006)
Two novel ligands for cerebral cannabinoid receptor (CB1), 1-(2,4-dichlorophenyl)-4-cyano-5-(4-methoxyphenyl)-N-(piperidin-1-yl) -1H-pyrazole-3-carboxamide (JHU75528) and 1-(2-bromophenyl)-4-cyano-5-(4- methoxyphenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carb
A new high-yield synthetic route to PET CB1 radioligands [ 11C]OMAR and its analogs
Gao, Mingzhang,Wang, Min,Zheng, Qi-Huang
experimental part, p. 3704 - 3709 (2012/07/17)
OMAR analogs reference standards and their corresponding desmethylated precursors were synthesized from substituted anilines either in 4 and 5 steps with 27-32% and 24-31% yield, or in 3 and 4 steps with 21-30% and 19-28% yield, respectively. [11/su
SUBSTITUTED N-(4-CYANO-1H-PYRAZOL-3-YL)METHYLAMINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF
-
Page/Page column 8, (2010/03/04)
The present invention relates to compounds corresponding to formula (I): Wherein X, R1, R2, R3 and R4 are as defined herein. The invention further relates to preparation and therapeutic use of these compounds.