32977-07-4

Upstream product

• 32977-06-3 1-(allyloxy)-3,5-dimethoxybenzene 
• 500-99-2 3,5-dimethoxyphenol 

Downstream Products

• 5273-94-9 1-(2,4,6-trimethoxyphenyl)-2-propene 
• 112890-03-6 2-Allyl-1-benzyloxy-3,5-dimethoxy-benzene 
• 371258-85-4 2-hydroxy-3-(prop-2-en-1-yl)-4,6-dimethoxybenzaldehyde 
• 371258-84-3 (S)-1-[2-hydroxy-4,6-dimethoxy-3-(2-propen-1-yl)-2-(4-methylphenylsulfinyl)]ethanone 
• 371258-87-6 (R)-5,7-dimethoxy-8-(2-propen-1-yl)-3-(4-methylphenylsulfinyl)-4H-1-benzopyran-4-one 
• 5273-96-1 (E)-1,3,5-trimethoxy-2-(prop-1-en-1-yl)benzene 
• 1463456-57-6 (E)-1,5-dimethoxy-2-(prop-1-en-1-yl)-3-(vinyloxy)benzene 
• 1463456-56-5 2-allyl-1-(2-chloroethoxy)-3,5-dimethoxybenzene 
• 112890-08-1 Methanesulfonic acid (2R,3S)-3-(2-benzyloxy-4,6-dimethoxy-benzyl)-2-methyl-oxiranylmethyl ester 
• 112890-05-8 (Z)-4-(2-Benzyloxy-4,6-dimethoxy-phenyl)-2-methyl-but-2-enoic acid ethyl ester 
• 112890-07-0 [(2R,3S)-3-(2-Benzyloxy-4,6-dimethoxy-benzyl)-2-methyl-oxiranyl]-methanol 
• 112890-06-9 (Z)-4-(2-Benzyloxy-4,6-dimethoxy-phenyl)-2-methyl-but-2-en-1-ol 
• 112890-04-7 (2-Benzyloxy-4,6-dimethoxy-phenyl)-acetaldehyde 
• 275816-91-6 5-(6-tert-butyldimethylsilyloxy-2,4-dimethoxyphenyl)-4-(4-methoxyphenyl)-1,2,4-pententriol 

Relevant academic research and scientific papers

An atom-economical and stereoselective domino synthesis of functionalised dienes

Open sesame: A direct synthesis of functionalised and stereodefined dienes, relying on a domino allylic alkylation/electrocyclic ring-opening sequence, is reported. This method allows concise access to doubly vinylogous esters. A further systematic study

Selective Claisen rearrangement and iodination for the synthesis of polyoxygenated allyl phenol derivatives

Allyl aryl ethers and allyl phenol derivatives were prepared starting from commercial or synthetized phenols. Either Williamson reaction or Et2AlCl catalyzed Claisen rearrangement was performed to obtain the polyoxygenated molecules. The pivotal allyl phenols were then modified by methylation, iodocyclization or electrophilic aromatic iodination to afford the polyoxygenated derivatives in good to excellent yields. Additionally, their antibacterial properties were also investigated against Gram-positive and Gram-negative bacteria.

Synthetic models related to methoxalen - CYP2A6 interactions. Dimethoxybenzofuran derivatives as potent and selective inhibitors of cyp2a6

The human CYP2A6 enzyme metabolizes several xenobiotics including nicotine, the addictive component in tobacco. Reduced activity of CYP2A6, either for genetic reasons or by administering inhibitors of CYP2A6, reduces tobacco smoking. The reported compound

A NOVEL ENANTIOSELECTIVE CYCLIZATION OF A CHIRAL EPOXIDE TO A BENZOFURAN SYSTEME

A convenient method has been established for the steroselective construction of a dihydrobenzofuran ring system found in several bioactive natural products.The final step of the synthesis involves the concerted and efficient intramolecular displacement of