32978-68-0Relevant academic research and scientific papers
Method of treating or preventing myocardial ischemia-reperfusion injury using NF-kB inhibitors
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Page/Page column 16-17, (2008/06/13)
The present invention concerns a method of treatment or prevention of myocardial ischemia-reperfusion injury by diagnosing that a person is in need of treatment or prevention of myocardial ischemia-reperfusion injury and administering a therapeutically ef
Substituted 4-hydroxyphenyl sulfonamides as pathway-selective estrogen receptor ligands
Sabatucci, Joseph P.,Ashwell, Mark A.,Trybulski, Eugene,O'Donnell, Mary-Margaret,Moore, William J.,Harnish, Douglas C.,Chadwick, Christopher C.
, p. 854 - 858 (2007/10/03)
The transcription factor nuclear factor-κB (NF-κB) is a key component in the onset of inflammation. We describe here a series of 4-hydroxyphenyl sulfonamide estrogen receptor (ER) ligands that selectively inhibit NK-κB transcriptional activity but are devoid of conventional estrogenic activity.
Methods of treating atherosclerosis using NF-kB inhibitors
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Page/Page column 16-17, (2008/06/13)
The present invention concerns a method of treating atherosclerosis by diagnosing that a person is in need of treatment for atherosclerosis and administering a therapeutically effective amount of a ligand which modulates NF-kB transcription factor by inte
Methods of treating inflammatory bowel disease using NF-kB inhibitors
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Page/Page column 17, (2010/02/11)
The present invention concerns a method of treating inflammatory bowel disease by diagnosing that a person is in need of treatment for inflammatory bowel disease and administering a therapeutically effective amount of a ligand which modulates NF-kB transc
USE OF ESTROGEN RECEPTOR LIGANDS FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE
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Page/Page column 39, (2008/06/13)
The present invention concerns a method of treating inflammatory bowel disease by diagnosing that a person is in need of treatment for inflammatory bowel disease and administering a therapeutically effective amount of a ligand which modulates NF-kB transc
METHOD OF TREATING RHEUMATOID ARTHRITIS USING NF-kB INHIBITORS
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Page/Page column 38, (2010/02/11)
The present invention concerns a method of treating rheumatoid arthritis by diagnosing that a person is in need of treatment for rheumatoid arthritis and administering a therapeutically effective amount of a ligand which modulates NF-kB transcription fact
METHODS OF TREATING ATHEROSCLEROSIS USING NF-kB INHIBITORS
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Page/Page column 40, (2008/06/13)
The present invention concerns a method of treating atherosclerosis by diagnosing that a person is in need of treatment for atherosclerosis and administering a therapeutically effective amount of a ligand which modulates NF-kB transcription factor by inte
Methods of treating rheumatoid arthritis using NF-kB inhibitors
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Page/Page column 17, (2008/06/13)
The present invention concerns a method of treating rheumatoid arthritis by diagnosing that a person is in need of treatment for rheumatoid arthritis and administering a therapeutically effective amount of a ligand which modulates NF-kB transcription fact
SUBSTITUTED DIHYDROPHENANTHRIDINESUL FONAMIDES
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Page 89-90, (2010/02/07)
This invention provides a compound of formulae (I) or (II) having the structure or a pharmaceutically acceptable salt thereof which are useful for the treatment of the inflammatory component of diseases and are particularly useful in treating atherosclerosis, myocardial infarction, congestive heart failure, inflammatory bowel disease, arthritis, type II diabetes, and autoimmune diseases such as multiple sclerosis and rheumatiod arthritis.
Polymers having N,N-disubstituted sulfonamide pendent groups and use thereof
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, (2008/06/13)
The invention relates to monomers of the formulae in which R1 is a (C1 -C20)alkyl, (C3 -C10)cycloalkyl, (C6 -C14)aryl or (C7 -C20) aralkyl radical, individu
