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32982-12-0

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32982-12-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 32982-12-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,9,8 and 2 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 32982-12:
(7*3)+(6*2)+(5*9)+(4*8)+(3*2)+(2*1)+(1*2)=120
120 % 10 = 0
So 32982-12-0 is a valid CAS Registry Number.

32982-12-0Downstream Products

32982-12-0Relevant articles and documents

Biosynthesis of fluopsin C, a copper-containing antibiotic from Pseudomonas aeruginosa

Patteson, Jon B.,Putz, Andrew T.,Tao, Lizhi,Simke, William C.,Bryant, L. Henry,Britt, R. David,Li, Bo

, p. 1005 - 1009 (2021/11/27)

Metal-binding natural products contribute to metal acquisition and bacterial virulence, but their roles in metal stress response are underexplored. We show that a five-enzyme pathway in Pseudomonas aeruginosa synthesizes a small-molecule copper complex, fluopsin C, in response to elevated copper concentrations. Fluopsin C is a broad-spectrum antibiotic that contains a copper ion chelated by two minimal thiohydroxamates. Biosynthesis of the thiohydroxamate begins with cysteine and requires two lyases, two iron-dependent enzymes, and a methyltransferase. The iron-dependent enzymes remove the carboxyl group and the a carbon from cysteine through decarboxylation, N-hydroxylation, and methylene excision. Conservation of the pathway in P. aeruginosa and other bacteria suggests a common role for fluopsin C in the copper stress response, which involves fusing copper into an antibiotic against other microbes.

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