32985-17-4

Usage

Chemical structure

1,1'-Dimethylmanganocene is an organometallic compound with a manganese atom sandwiched between two cyclopentadienyl rings, each with a methyl group attached.

Application

It is used as a catalyst in organic synthesis reactions.

Potential applications

It has been studied for its potential applications in medicinal chemistry and materials science.

Reactivity

The compound exhibits interesting reactivity and selectivity in various organic transformations.

Synthesis

It is a valuable tool in the development of new methods for the synthesis of complex molecules.

Therapeutic properties

It has been investigated for its potential therapeutic properties.

Cancer inhibition

It has been shown to inhibit the growth of cancer cells.

Neurotransmitter modulation

It has the ability to modulate the activity of neurotransmitter receptors.

Research significance

1,1'-Dimethylmanganocene represents an important class of organometallic compounds with diverse applications in chemical and biomedical research.

InChI:InChI=1/2C6H7.Mn/c2*1-6-4-2-3-5-6;/h2*2-5H,1H3;/q-5;-1;

Upstream product

• 92421-50-6 (η5-methylcyclopentadienyl)(μ-chloro)(tetrahydrofuran)manganese(II) dimer 

Downstream Products

• 223424-72-4 (1,2-bis(dimethylphosphino)ethane)(η(5)-methylcyclopentadienyl)(phenylethynyl)manganese(II) 
• 177283-11-3 bis(1,2-bis(dimethylphosphino)ethane)bis(phenylethynyl)manganese(II) 
• 223424-74-6 (1,2-bis(dimethylphosphino)ethane)(η(5)-methylcyclopentadienyl)(phenylvinylidene)manganese(I) 
• 223424-75-7 bis[(1,2-bis(dimethylphosphino)ethane)(η(5)-methylcyclopentadienyl)manganese(I)](μ-2,3-diphenylbutadien-1,4-diylidene) 

Relevant academic research and scientific papers

Monocyclopentadienyl compounds of manganese(II). Synthesis, structure, magnetism, and NMR spectra

A series of 13 manganese(II) half-sandwich compounds [(RnCp)MnXL]2, type L, and (Rcp)MnXL2, type K, have been prepared on different routes. These routes include the new starting materials Mn(DME)2I2 and [Mn3I6(AsEt3)4n. In general, K is favored only when small powerful donor ligands are used. In solution K and L are in equilibrium when R = Me, X = I, and L = PMe3. Byproducts of low solubility may force the equilibrium entirely to K, e.g., for R = H, X = I, and L = PMe3. A systematic paramagnetic NMR study shows that the compounds may be characterized easily. In particular, the distinction between K and L, the delocalization of unpaired electrons, and hyperconjugative effects in the phosphine-transition-metal bonding are shown. According to the NMR data and to solid-state magnetic measurements all compounds have five unpaired electrons per manganese at room temperature. For [Mecp)MnX(PEt3)]2 (X - Cl (2), X = Br (3), = I (4)) the magnetism has been followed down to 1.25 K, and antiferromagnetic interaction with J = -4.8, -5.0, and -4.7 cm-1 has been found. The J values are shown to be typical for superexchange in high-spin maganese(II) dimers. As determined by X-ray crystallography 2, 3, and 4 are halogen-bridged centrosymmetric dimers with pseudotetrahedral metal centers. Crystals of 2 and 3 are orthorhombic, space group Pbca, with a = 13.691 (3)/13.869 (1) ?, b = 15.314 (2)/15.248 (1) ?, c = 14.402 (3)/14.640 (1) ?, V = 3019.6/3074.8 ?3, and dcalcd = 1.265/1.435 g cm-3 for Z = 4. Refinement converged at R = 0.055/0.046 for 156/136 refined parameters and 1611/1572 observables. 4 is monoclinic, space group P21/c, with a = 15.099 (4) ?, b = 15.365 (3) ?, c = 14.576 (4) ?, β = 108.11 (2)°, V = 3214.1 ?3, and dcald = 1.567 g cm-3 for Z = 4. Refinement converged at R = 0.071 for 227 refined parameters and 2697 observed reflections. There is a clear halogen dependence for the geometry of the central Mn2X2 unit. All distances and the angle X-Mn-X increase on going from Cl to I while Mn-X-Mn* decreases. The latter effect is attributed to increasing halogen repulsion.