Welcome to LookChem.com Sign In|Join Free
  • or

32986-56-4

Post Buying Request

32986-56-4 Suppliers

Recommended suppliersmore

Product FOB Price Min.Order Supply Ability Supplier
bulk raw material API Tobramycin base ( micronized) Non-sterile 32986-56-4
Cas No: 32986-56-4
No Data 1 Kilogram 200 Kilogram/Month Josun International Limited Contact Supplier
Tobramycin base
Cas No: 32986-56-4
No Data 100 Gram Metric Ton/Day Hangzhou Dawn Ray Pharmaceutical Co.,Ltd Contact Supplier
High purity Various Specifications tobramycin CAS:32986-56-4
Cas No: 32986-56-4
USD $ 100.0-500.0 / Gram 1 Gram 99999 Gram/Year Hangzhou Dingyan Chem Co., Ltd Contact Supplier
Tobramycin CAS:32986-56-4 Safe delivery Free of customs clearance
Cas No: 32986-56-4
USD $ 1.0-10.0 / Kilogram 1 Kilogram 5000 Kilogram/Month WUHAN MULEI NEW MATERIAL CO., LTD Contact Supplier
Tobramycin
Cas No: 32986-56-4
No Data 10 Milligram Amadis Chemical Co., Ltd. Contact Supplier
High quality Factory supply Antibiotic API 98% Tobramycin Powder
Cas No: 32986-56-4
USD $ 1335.0-1349.0 / Kilogram 100 Kilogram 100000 Kilogram/Year Xi'an Quanao Biotech Co., Ltd. Contact Supplier
Supply 32986-56-4 Praziquantel /lowest price 32986-56-4 /Tobramycin hot sale
Cas No: 32986-56-4
No Data 100 Gram 1 Metric Ton/Month Hangzhou J&H Chemical Co., Ltd. Contact Supplier
Tobramycin (base and/or unspecified salts)
Cas No: 32986-56-4
No Data No Data No Data Chemwill Asia Co., Ltd. Contact Supplier
Tobramycin
Cas No: 32986-56-4
No Data 1 Gram Metric Ton/Day Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
Tobramycin
Cas No: 32986-56-4
USD $ 1.0-1.0 / Kilogram 1 Kilogram 2000 Metric Ton/Year Henan Sinotech Import&Export Corporation Contact Supplier

32986-56-4 Usage

Uses

Single factor antibiotic comprising about 10% of nebramycin, the aminoglycosidic antibiotic complex produced by Streptomyces tenebrarius. Antibacterial

Chemical Properties

White Powder

Uses

Tobramycin is an aminoglycoside antibiotic.

Uses

Antihypertensive

Definition

ChEBI: A amino cyclitol glycoside that is kanamycin B lacking the 3-hydroxy substituent from the 2,6-diaminoglucose ring.

Uses

antibacterial, inhibits protein synthesis
InChI:InChI=1/C20H41N5O7/c21-5-8-1-7(10(22)4-13(8)27)2-9-11(23)3-12(24)19(16(9)28)32-20-18(30)15(25)17(29)14(6-26)31-20/h7-20,26-30H,1-6,21-25H2

32986-56-4 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
TCI America (T2503)  Tobramycin  >94.0%(T) 32986-56-4 25g 2,990.00CNY Detail
TCI America (T2503)  Tobramycin  >94.0%(T) 32986-56-4 5g 585.00CNY Detail

32986-56-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name tobramycin

1.2 Other means of identification

Product number -
Other names nebicina

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:32986-56-4 SDS

32986-56-4Synthetic route

fosfomycin
23155-02-4

fosfomycin

tobramycin
32986-56-4

tobramycin

tobramycin sulfate

tobramycin sulfate

tobramycin
32986-56-4

tobramycin

Conditions
ConditionsYield
Stage #1: tobramycin sulfate
Stage #2: With trifluoroacetic acid In water
tobramycin
32986-56-4

tobramycin

1,3-di(tert-butyloxycarbonyl)-2-(trifluoromethylsulfonyl)guanidine
207857-15-6

1,3-di(tert-butyloxycarbonyl)-2-(trifluoromethylsulfonyl)guanidine

guanidinoboc10-tobramycin

guanidinoboc10-tobramycin

Conditions
ConditionsYield
With triethylamine In 1,4-dioxane; water at 20℃; for 72h;100%
tobramycin
32986-56-4

tobramycin

1,3-di(tert-butyloxycarbonyl)-2-(trifluoromethylsulfonyl)guanidine
207857-15-6

1,3-di(tert-butyloxycarbonyl)-2-(trifluoromethylsulfonyl)guanidine

C73H127N15O29
290360-48-4

C73H127N15O29

Conditions
ConditionsYield
With triethylamine In 1,4-dioxane; water at 20℃; for 72h;100%
tobramycin
32986-56-4

tobramycin

O-3-azido-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[2,6-diazido-2,3,6-trideoxy-α-D-ribo-hexopyranosyl-(1→4)]-1,3-diazido-1,2,3-trideoxy-D-myo-inositol
468065-22-7

O-3-azido-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[2,6-diazido-2,3,6-trideoxy-α-D-ribo-hexopyranosyl-(1→4)]-1,3-diazido-1,2,3-trideoxy-D-myo-inositol

Conditions
ConditionsYield
With TEA; triflic azide; copper(II) sulfate In methanol; dichloromethane100%
With triflic azide; triethylamine; zinc(II) chloride In methanol; dichloromethane; water at 20℃;92%
With triflic azide; copper(II) sulfate; triethylamine83%
With triflic azide; triethylamine; zinc(II) chloride In methanol; dichloromethane; water Inert atmosphere;
With triflic azide; zinc(II) chloride In methanol; dichloromethane; water Inert atmosphere;
tobramycin
32986-56-4

tobramycin

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

di-tert-butyl ((1S,3R,4S,5S,6R)-4-(((2S,3R,4S,5S,6R)-4-((tert-butoxycarbonyl)amino)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-6-(((2R,3R,5S,6R)-3-((tert-butoxycarbonyl)amino)-6-(((tert-butoxycarbonyl)methyl)-5-hydroxytetrahydro-2H-pyran-2-yl)oxy)-5-hydroxycyclohexane-1,3-diyl)dicarbamate)
172950-21-9

di-tert-butyl ((1S,3R,4S,5S,6R)-4-(((2S,3R,4S,5S,6R)-4-((tert-butoxycarbonyl)amino)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-6-(((2R,3R,5S,6R)-3-((tert-butoxycarbonyl)amino)-6-(((tert-butoxycarbonyl)methyl)-5-hydroxytetrahydro-2H-pyran-2-yl)oxy)-5-hydroxycyclohexane-1,3-diyl)dicarbamate)

Conditions
ConditionsYield
With triethylamine In water at 60℃; for 0.666667h;98%
With triethylamine In methanol; water at 55℃;98%
With triethylamine In methanol; water at 55℃;97%
tobramycin
32986-56-4

tobramycin

5-benzoyl-3-(cyclopent-1-en-1-yl)-5-phenyl-1,5-dihydro-4H-pyrazol-4-one

5-benzoyl-3-(cyclopent-1-en-1-yl)-5-phenyl-1,5-dihydro-4H-pyrazol-4-one

C25H41N5O10

C25H41N5O10

Conditions
ConditionsYield
In dimethyl sulfoxide at 20℃; for 24h; Solvent;92%
tobramycin
32986-56-4

tobramycin

benzyl chloroformate
501-53-1

benzyl chloroformate

1,3,2',6',3''-pentakis(N-benzyloxycarbonyl)-3'-deoxykanamycin B
61093-69-4

1,3,2',6',3''-pentakis(N-benzyloxycarbonyl)-3'-deoxykanamycin B

Conditions
ConditionsYield
With sodium carbonate90%
With sodium carbonate In water
With sodium carbonate In acetone at 0℃;
tobramycin
32986-56-4

tobramycin

N-(benzyloxycarbonyloxy)phthalimide
65162-83-6

N-(benzyloxycarbonyloxy)phthalimide

6'-N-benzyloxycarbonyltobramycin

6'-N-benzyloxycarbonyltobramycin

Conditions
ConditionsYield
With potassium carbonate In methanol; water at 20℃; for 18h;64%
azidoacetic acid succinimidyl ester

azidoacetic acid succinimidyl ester

tobramycin
32986-56-4

tobramycin

6'-N-azidoacetyl tobramycin
1220984-19-9

6'-N-azidoacetyl tobramycin

Conditions
ConditionsYield
With potassium carbonate In methanol; water for 20h;63%
tobramycin
32986-56-4

tobramycin

magnesium acetate
142-72-3, 92123-19-8

magnesium acetate

3-N-acetyltobramycin
68244-01-9

3-N-acetyltobramycin

Conditions
ConditionsYield
With Tmed buffer; ATP In water for 12h; aminoglycoside phosphotransferase;62%
tobramycin
32986-56-4

tobramycin

N-<<(benzyloxy)carbonyl>oxy>-5-norbornene-2,3-dicarboximide
62210-73-5

N-<<(benzyloxy)carbonyl>oxy>-5-norbornene-2,3-dicarboximide

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

C36H59N5O15

C36H59N5O15

Conditions
ConditionsYield
Stage #1: tobramycin With zinc(II) acetate dihydrate In dimethyl sulfoxide at 21℃;
Stage #2: N-<<(benzyloxy)carbonyl>oxy>-5-norbornene-2,3-dicarboximide In dimethyl sulfoxide at 21℃; for 24h;
Stage #3: di-tert-butyl dicarbonate In dimethyl sulfoxide at 21℃; for 4h;
57%
tobramycin
32986-56-4

tobramycin

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

C33H61N5O15

C33H61N5O15

Conditions
ConditionsYield
Stage #1: tobramycin With zinc(II) acetate dihydrate In dimethyl sulfoxide at 21℃;
Stage #2: di-tert-butyl dicarbonate In dimethyl sulfoxide at 21℃; for 5h;
53%
tobramycin
32986-56-4

tobramycin

N-[(S)-4-benzyloxycarbonylamino-2-hydroxy-butyryloxy]succinimide
40371-52-6

N-[(S)-4-benzyloxycarbonylamino-2-hydroxy-butyryloxy]succinimide

6'-N-CbzAHB tobramycin
1312471-07-0

6'-N-CbzAHB tobramycin

Conditions
ConditionsYield
Stage #1: tobramycin With zinc diacetate In water; N,N-dimethyl-formamide at 20℃; for 16h;
Stage #2: N-[(S)-4-benzyloxycarbonylamino-2-hydroxy-butyryloxy]succinimide In water; N,N-dimethyl-formamide for 24h;
31%
tobramycin
32986-56-4

tobramycin

2,4-dinitrophenylthioglycolic acid N-hydroxy succinimide ester
93801-70-8

2,4-dinitrophenylthioglycolic acid N-hydroxy succinimide ester

N-{(2R,3S,5R,6R)-5-Amino-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-((2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2-hydroxy-cyclohexyloxy]-3-hydroxy-tetrahydro-pyran-2-ylmethyl}-2-(2,4-dinitro-phenylsulfanyl)-acetamide
93801-67-3

N-{(2R,3S,5R,6R)-5-Amino-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-((2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2-hydroxy-cyclohexyloxy]-3-hydroxy-tetrahydro-pyran-2-ylmethyl}-2-(2,4-dinitro-phenylsulfanyl)-acetamide

Conditions
ConditionsYield
In water; N,N-dimethyl-formamide at 0℃; for 2h; pH=10.76;28.3%
tobramycin
32986-56-4

tobramycin

acetic anhydride
108-24-7

acetic anhydride

A

1,3,2',6',3''-penta-N-acetyltobramycin
33985-51-2

1,3,2',6',3''-penta-N-acetyltobramycin

B

1,2',6',3''-tetra-N-acetyltobramycin

1,2',6',3''-tetra-N-acetyltobramycin

C

1,3,2',6'-tetra-N-acetyltobramycin

1,3,2',6'-tetra-N-acetyltobramycin

D

1,2',6'-tri-N-acetyltobramycin

1,2',6'-tri-N-acetyltobramycin

Conditions
ConditionsYield
In methanol for 0.166667h; Ambient temperature; Yields of byproduct given;A 26.9%
B n/a
C n/a
D n/a
In methanol for 0.166667h; Ambient temperature; Yields of byproduct given;A n/a
B 7.4%
C n/a
D n/a
In methanol for 0.166667h; Ambient temperature; Yield given. Yields of byproduct given;
tobramycin
32986-56-4

tobramycin

N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

[2-[4-amino-3-(4-amino-3,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-6-benzyloxycarbonylamino-2-hydroxy-cyclohexyloxy]-6-(benzyloxycarbonylamino-methyl)-5-hydroxy-tetrahydro-pyran-3-yl]-carbamic acid benzyl ester

[2-[4-amino-3-(4-amino-3,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-6-benzyloxycarbonylamino-2-hydroxy-cyclohexyloxy]-6-(benzyloxycarbonylamino-methyl)-5-hydroxy-tetrahydro-pyran-3-yl]-carbamic acid benzyl ester

Conditions
ConditionsYield
Stage #1: tobramycin With zinc diacetate In dimethyl sulfoxide for 12h;
Stage #2: N-(Benzyloxycarbonyloxy)succinimide In dimethyl sulfoxide for 2h;
25%
tobramycin
32986-56-4

tobramycin

[[(tetramethyl-4,4-difluoro-4-bora-3a,4a-diazaindacene)methyl]phenoxy]ethyl (4-nitrophenyl) carbonate

[[(tetramethyl-4,4-difluoro-4-bora-3a,4a-diazaindacene)methyl]phenoxy]ethyl (4-nitrophenyl) carbonate

C40H58BF2N7O12

C40H58BF2N7O12

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide Darkness;17%
tobramycin
32986-56-4

tobramycin

N-acetyl-DL-homocysteinethiolactone
1195-16-0, 768351-04-8

N-acetyl-DL-homocysteinethiolactone

2-Acetylamino-N-{(2R,3S,5R,6R)-5-amino-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-((2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2-hydroxy-cyclohexyloxy]-3-hydroxy-tetrahydro-pyran-2-ylmethyl}-4-mercapto-butyramide

2-Acetylamino-N-{(2R,3S,5R,6R)-5-amino-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-((2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2-hydroxy-cyclohexyloxy]-3-hydroxy-tetrahydro-pyran-2-ylmethyl}-4-mercapto-butyramide

Conditions
ConditionsYield
In water for 30h; pH=10.12-10.25; Yield given;
tobramycin
32986-56-4

tobramycin

N-acetyl-DL-homocysteinethiolactone
1195-16-0, 768351-04-8

N-acetyl-DL-homocysteinethiolactone

α-bromoacetophenone
70-11-1

α-bromoacetophenone

C32H52N6O12S

C32H52N6O12S

Conditions
ConditionsYield
With hydrogenchloride 1.) 20110.12-10.25, 30 min; 2.) pH=7.5, water, THF, 0 deg C, 2 h; Yield given. Multistep reaction;
tobramycin
32986-56-4

tobramycin

acetic anhydride
108-24-7

acetic anhydride

penta-N-penta-O-acetyltobramycin
144727-30-0

penta-N-penta-O-acetyltobramycin

Conditions
ConditionsYield
With pyridine
tobramycin
32986-56-4

tobramycin

benzyl chloroformate
501-53-1

benzyl chloroformate

6'-N-benzyloxycarbonyltobramycin

6'-N-benzyloxycarbonyltobramycin

Conditions
ConditionsYield
With benzotriazol-1-ol; triethylamine 1.) dioxane, RT, 30 min, 2.) dioxane, water, RT, 20 h; Yield given. Multistep reaction;
tobramycin
32986-56-4

tobramycin

C28H49N10O15P

C28H49N10O15P

Conditions
ConditionsYield
at 37℃; aminoglycoside-4'-nucleotidyltransferaze of Bacillus brevis, MgCl2, potassium phosphate buffer (pH 6.0);
tobramycin
32986-56-4

tobramycin

(2S,3R,5S,6R)-4-Azido-2-[(2S,3R,4S,6R)-4,6-diazido-3-((2R,3R,5S,6R)-3-azido-6-azidomethyl-5-hydroxy-tetrahydro-pyran-2-yloxy)-2-hydroxy-cyclohexyloxy]-6-hydroxymethyl-tetrahydro-pyran-3,5-diol

(2S,3R,5S,6R)-4-Azido-2-[(2S,3R,4S,6R)-4,6-diazido-3-((2R,3R,5S,6R)-3-azido-6-azidomethyl-5-hydroxy-tetrahydro-pyran-2-yloxy)-2-hydroxy-cyclohexyloxy]-6-hydroxymethyl-tetrahydro-pyran-3,5-diol

Conditions
ConditionsYield
With triflic azide; triethylamine; zinc(II) chloride In methanol; dichloromethane; water
tobramycin
32986-56-4

tobramycin

3,2',6'-tris(N-benzyloxycarbonyl)-3'-deoxy-3''-N-(trifluoroacetyl)kanamycin B
103842-08-6

3,2',6'-tris(N-benzyloxycarbonyl)-3'-deoxy-3''-N-(trifluoroacetyl)kanamycin B

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: Zn(OAc)2*2H2O / dimethylsulfoxide / 12 h
1.2: 25 percent / dimethylsulfoxide / 2 h
2.1: 60 percent / dimethylsulfoxide / 2 h
View Scheme
tobramycin
32986-56-4

tobramycin

C21H43N7O11

C21H43N7O11

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: Zn(OAc)2*2H2O / dimethylsulfoxide / 12 h
1.2: 25 percent / dimethylsulfoxide / 2 h
2.1: 60 percent / dimethylsulfoxide / 2 h
3.1: 11 mg / tetrahydrofuran; H2O / 96 h / 20 °C
4.1: aq. NaOH / methanol / 20 h
5.1: 4.5 mg / H2 / 10 percent Pd/C / dioxane; H2O; acetic acid / 0.67 h
View Scheme
tobramycin
32986-56-4

tobramycin

C53H67N7O19
533923-31-8

C53H67N7O19

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: Zn(OAc)2*2H2O / dimethylsulfoxide / 12 h
1.2: 25 percent / dimethylsulfoxide / 2 h
2.1: 60 percent / dimethylsulfoxide / 2 h
3.1: 11 mg / tetrahydrofuran; H2O / 96 h / 20 °C
4.1: aq. NaOH / methanol / 20 h
View Scheme
tobramycin
32986-56-4

tobramycin

C62H70F3N7O21
533923-30-7

C62H70F3N7O21

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: Zn(OAc)2*2H2O / dimethylsulfoxide / 12 h
1.2: 25 percent / dimethylsulfoxide / 2 h
2.1: 60 percent / dimethylsulfoxide / 2 h
3.1: 11 mg / tetrahydrofuran; H2O / 96 h / 20 °C
View Scheme

Please post your buying leads,so that our qualified suppliers will soon contact you!

*Required Fields