32988-39-9 Usage
Uses
Used in Scientific Research:
3-NITRO-D-TYROSINE is used as a biomarker for [measuring nitrosative stress levels] in organisms, as it indicates the presence of reactive nitrogen species involved in various physiological and pathophysiological processes.
Used in Neurodegenerative Disorder Studies:
3-NITRO-D-TYROSINE is used as a research tool for [investigating neurodegenerative disorders], given its relevance to the study of conditions such as Alzheimer's and Parkinson's disease, where oxidative and nitrosative stress play a significant role.
Used in Cardiovascular Disease Research:
3-NITRO-D-TYROSINE is used as a marker for [evaluating the impact of nitrosative stress on cardiovascular health], helping researchers understand the mechanisms underlying heart diseases and stroke.
Used in Cancer Research:
3-NITRO-D-TYROSINE is used as a bioindicator for [exploring the role of reactive nitrogen species in cancer development and progression], assisting in the identification of potential therapeutic targets and the assessment of treatment efficacy.
Check Digit Verification of cas no
The CAS Registry Mumber 32988-39-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,9,8 and 8 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 32988-39:
(7*3)+(6*2)+(5*9)+(4*8)+(3*8)+(2*3)+(1*9)=149
149 % 10 = 9
So 32988-39-9 is a valid CAS Registry Number.
32988-39-9Relevant academic research and scientific papers
Inhibitory effect of isoflavones on peroxynitrite-mediated low-density lipoprotein oxidation.
Lai, Hsi-Huai,Yen, Gow-Chin
, p. 22 - 28 (2007/10/03)
Peroxynitrite, a potent oxidant formed in vivo from the reaction of nitric oxide with superoxide, can mediate low-density liprotein (LDL) oxidation which is thought to increase the risk of atherosclerosis. This study investigates the inhibitory effect of the isoflavones, genistein and daidzein, together with their glycosidic forms, genistin and daidzin, on the peroxynitrite-mediated LDL oxidation and nitration of tyrosine. Genistein and daidzein were observed to dose-dependently inhibit peroxynitrite-mediated LDL oxidation, while their glucoside conjugates showed less activity. Moreover, all the isoflavones used in this study were found to be potent peroxynitrite scavengers, preventing the nitration of tyrosine. The ability of the isoflavones at 50 microM to decrease the tyrosine nitration induced by peroxynitrite (1 mM) was in the ratios of genistein (49%), daidzein (40%), daidzin (41%) and genistin (42%) when compared to the control (tyrosine incubated only with peroxynitrite). These results suggest that an intake of isoflavones could contribute to protecting against cardiovascular diseases and chronic inflammatory diseases.
