32991-06-3

Basic information

• Product Name: Ethenamine, 2-(2-chloro-6-nitrophenyl)-N,N-dimethyl-, (E)-
• Synonyms: (E)-2-chloro-β-dimethylamino-6-nitrostyrene;trans-6-chloro-β-dimethylamino-2-nitrostyrene
• CAS NO: 32991-06-3
• Molecular Formula: C10H11ClN2O2
• Molecular Weight: 226.663
• Mol File: 32991-06-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 343.9±37.0 °C(Predicted)
• Density: 1.273±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Ethenamine, 2-(2-chloro-6-nitrophenyl)-N,N-dimethyl-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethenamine, 2-(2-chloro-6-nitrophenyl)-N,N-dimethyl-, (E)-(32991-06-3)
• EPA Substance Registry System: Ethenamine, 2-(2-chloro-6-nitrophenyl)-N,N-dimethyl-, (E)-(32991-06-3)

Safety Data

• Hazardous Substances Data: 32991-06-3(Hazardous Substances Data)

Upstream product

• 83-42-1 6-chloro-2-nitrotoluene 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 

Downstream Products

• 25235-85-2 4-chloro-1H-indole 
• 2519-61-1 4-chloroindole-3-acetic acid 
• 2447-15-6 4-chloroindole-3-acetonitrile 
• 19077-78-2 Methyl 4-chloro-3-indoleacetate 

Relevant articles and documents

Microwave assisted Leimgruber-Batcho reaction for the preparation of indoles, azaindoles and pyrroylquinolines

The development of enhanced conditions for Lewis acid catalysed Leimgruber-Batcho indole synthesis using microwave acceleration is described. This approach has permitted the preparation of a variety of heteroaromatic enamine intermediates in good yield and high purities. Subsequent catalytic hydrogenation reactions, under various conditions including the use of a solid-phase encapsulated catalyst, furnish the corresponding indole derivatives in good yields.

7-Nitroindoles

7-Aminoindole is prepared from a 7-nitroindole, which in turn is prepared from a halo-substituted β-dialkylamino-2-nitrostyrene.