329914-22-9

Upstream product

• 329914-21-8 (2S,5S,6R,12S,13S,14R)-17-Benzyloxy-1-(tert-butyl-dimethyl-silanyloxy)-2,6,12,14-tetramethyl-5,13-bis-triethylsilanyloxy-heptadec-7-yn-9-one 
• 329914-20-7 (5R,6S,7S)-N-methyl,N-methoxy-9-benzyloxy-4,5-dimethyl-5-(triethylsilyl)oxy-2-nonanecarboxamide 
• 329914-13-8 (2S,5S,6R,12S,13S,14R)-17-Benzyloxy-1-(tert-butyl-dimethyl-silanyloxy)-2,6,12,14-tetramethyl-5,13-bis-triethylsilanyloxy-heptadecan-9-one 
• 329914-19-4 (5R,6S,7S)-N-methyl,N-methoxy-9-benzyloxy-4,5-dimethyl-5-(triethylsilyl)oxy-2-nonynecarboxamide 
• 329914-11-6 (2S,5S,6R,12S,13S,14R)-2,6,12,14-tetramethyl-1-(tert-butyldimethylsilyl)oxy-5,13-(triethylsilyl)oxy-17-benzyloxy-7,10-heptadecyn-9-one 
• 329914-10-5 (2S,5S,6R,12S,13S,14R)-2,6,12,14-tetramethyl-1-(tert-butyldimethylsilyl)oxy-5,13-(triethylsilyl)oxy-17-benzyloxy-7,10-heptadecyn-9-ol 

Downstream Products

• 329914-24-1 (2S,3S,6R,8S,9R)-2-((R)-4-Benzyloxy-1-methyl-butyl)-3,9-dimethyl-8-((S)-3-methyl-pent-4-enyl)-1,7-dioxa-spiro[5.5]undecane 
• 329914-23-0 (S)-4-[(2S,3R,6R,8S,9S)-8-((R)-4-Benzyloxy-1-methyl-butyl)-3,9-dimethyl-1,7-dioxa-spiro[5.5]undec-2-yl]-2-methyl-butyraldehyde 

Relevant academic research and scientific papers

Synthesis of a C1-C21 subunit of the protein phosphatase inhibitor tautomycin: A formal total synthesis

The synthesis of a C1-C21 subunit of tautomycin is described. The convergent route employs enantioenriched allenylstannane and zinc reagents derived from (S)-3-butyn-2-ol methanesulfonate. These reagents react with appropriate aldehyde segments to yield s