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(S)-{2-[3-(4-cyano-3-fluorobenzyl)-3H-imidazol-4-yl]ethyl}-[1-(7-hydroxynaphthalen-1-yl)-2-oxopyrrolidin-3-yl]carbamic acid tert-butyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

330213-85-9

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  • (S)-{2-[3-(4-cyano-3-fluorobenzyl)-3H-imidazol-4-yl]ethyl}-[1-(7-hydroxynaphthalen-1-yl)-2-oxopyrrolidin-3-yl]carbamic acid tert-butyl ester

    Cas No: 330213-85-9

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  • (S)-{2-[3-(4-cyano-3-fluorobenzyl)-3H-imidazol-4-yl]ethyl}-[1-(7-hydroxynaphthalen-1-yl)-2-oxopyrrolidin-3-yl]carbamic acid tert-butyl ester

    Cas No: 330213-85-9

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330213-85-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 330213-85-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,0,2,1 and 3 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 330213-85:
(8*3)+(7*3)+(6*0)+(5*2)+(4*1)+(3*3)+(2*8)+(1*5)=89
89 % 10 = 9
So 330213-85-9 is a valid CAS Registry Number.

330213-85-9Downstream Products

330213-85-9Relevant articles and documents

Inhibitors of prenyl-protein transferase

-

, (2008/06/13)

The present invention is directed to macrocyclic compounds which inhibit prenyl-protein transferase (FTase) and the prenylation of the oncogene protein Ras. The invention is further directed to chemothera-peutic compositions containing the compounds of this invention and methods for inhibiting prenyl-protein transferase and the prenylation of the oncogene protein Ras.

3-Aminopyrrolidinone farnesyltransferase inhibitors: Design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency

Bell, Ian M.,Gallicchio, Steven N.,Abrams, Marc,Beese, Lorena S.,Beshore, Douglas C.,Bhimnathwala, Hema,Bogusky, Michael J.,Buser, Carolyn A.,Culberson, J. Christopher,Davide, Joseph,Ellis-Hutchings, Michelle,Fernandes, Christine,Gibbs, Jackson B.,Graham, Samuel L.,Hamilton, Kelly A.,Hartman, George D.,Heimbrook, David C.,Homnick, Carl F.,Huber, Hans E.,Huff, Joel R.,Kassahun, Kelem,Koblan, Kenneth S.,Kohl, Nancy E.,Lobell, Robert B.,Lynch Jr., Joseph J.,Robinson, Ronald,Rodrigues, A. David,Taylor, Jeffrey S.,Walsh, Eileen S.,Williams, Theresa M.,Zartmant, C. Blair

, p. 2388 - 2409 (2007/10/03)

A series of macrocyclic 3-aminopyrrolidinone farnesyltransferase inhibitors (FTIs) has been synthesized. Compared with previously described linear 3-aminopyrrolidinone FTIs such as compound 1, macrocycles such as 49 combined improved pharmacokinetic prope

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