330438-39-6Relevant academic research and scientific papers
Imidazole-based ligands of the Src SH2 protein
Deprez, Pierre,Mandine, Eliane,Vermond, Annie,Lesuisse, Dominique
, p. 1287 - 1289 (2002)
Starting from known Src SH2 inhibitors incorporating five-membered heterocycles or benzamide scaffolds, we prepared tetrasubstituted imidazole compounds able to interact with the pY, pY+1 and pY+3 binding sites of the Src SH2 protein. The synthesis and bi
