330566-95-5Relevant academic research and scientific papers
Synthesis and antimicrobial activity of some 2-[p-substituted-phenyl]benzoxazol-5-yl-arylcarboxyamides
Temiz-Arpaci, Oezlem,Aki-Sener, Esin,Yalcin, Ismail,Altanlar, Nurten
, p. 283 - 288 (2002)
New 2-[p-substituted-phenyl]benzoxazol-5-yl-arylcarboxyamides derivatives have been synthesized by reacting 5-amino-2-[p-substituted-phenyl]benzoxazoles with substituted-arylcarboxylic acid chlorides. The structures of the synthesized compounds were confirmed by IR and 1H NMR spectral data. Antimicrobial activities of the compounds were investigated using the two-fold serial dilution technique against different Gram-positive and Gram-negative bacteria and the yeast C. albicans in comparison with standard drugs. Microbiological results indicated that the synthesized compounds possess a broad spectrum of activity, having an MIC value of 25-200 μg/mL at molar concentration values of 3.45 × 10-5 and 5.74 × 10-4 against the tested microorganisms.
