330669-97-1

Basic information

• Product Name: (R)-1-(3,4-difluoro-benzylamino)-3-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-phenoxy]-propan-2-ol
• CAS NO: 330669-97-1
• Molecular Weight: 428.411
• Mol File: 330669-97-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-1-(3,4-difluoro-benzylamino)-3-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-phenoxy]-propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-(3,4-difluoro-benzylamino)-3-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-phenoxy]-propan-2-ol(330669-97-1)
• EPA Substance Registry System: (R)-1-(3,4-difluoro-benzylamino)-3-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-phenoxy]-propan-2-ol(330669-97-1)

Safety Data

• Hazardous Substances Data: 330669-97-1(Hazardous Substances Data)

Upstream product

• 330670-95-6 (R)-6-fluoro-3-(4-oxiranylmethoxy-phenyl)-benzo[d]isoxazole 
• 72235-53-1 3,4-difluorobenzylamine 

Relevant articles and documents

Benzisoxazolyl-, pyridoisoxazolyl- and benzthienyl-phenoxy derivatives useful as D4 antagonists

The compounds are of the class of benzisoxazolyl-, pyridoisoxazolyl- and benzthienyl-phenoxy derivatives, useful as D4 antagonists. Said compounds are useful for the treatment of medical conditions mediated by inhibition of D4 receptor. These conditions comprise, for example, Attention Deficit Hyperactivity Disorder, Obsessive-Compulsive Disorder, Psychoses, Substance Abuse, Substance Dependence, Parkinson's Disease, Parkinsonism, Tardive Diskinesia, Gilles de la Tourette Syndrome, Conduct Disorder, and Oppositional Defiant Disorder. A further aspect of the invention is to provide a pharmaceutical composition, intermediates, and a method of making said class of compounds.