330786-25-9

Basic information

• Product Name: PCI 29732
• Synonyms: PCI 29732;4-Amino-1-cyclopentyl-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine;1-Cyclopentyl-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
• CAS NO: 330786-25-9
• Molecular Formula: C₂₂H₂₁N₅O
• Molecular Weight: 371.43504
• Mol File: 330786-25-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 599.6±50.0 °C(Predicted)
• Appearance: /
• Density: 1.36±0.1 g/cm3(Predicted)
• PKA: 4.24±0.30(Predicted)
• CAS DataBase Reference: PCI 29732(CAS DataBase Reference)
• NIST Chemistry Reference: PCI 29732(330786-25-9)
• EPA Substance Registry System: PCI 29732(330786-25-9)

Safety Data

• Hazardous Substances Data: 330786-25-9(Hazardous Substances Data)

Usage

Description

PCI 29732 is a chemical compound that functions as an anti-inflammatory drug, primarily used in the treatment of inflammatory diseases such as rheumatoid arthritis and lymphoma. It operates by inhibiting Bruton’s tyrosine kinase (BTK), a key enzyme in the activation of pro-inflammatory cells, thereby effectively reducing inflammation and alleviating disease symptoms. PCI 29732 is currently in clinical trials to further assess its therapeutic potential.

Uses

Used in Pharmaceutical Industry:
PCI 29732 is used as an anti-inflammatory agent for the treatment of inflammatory diseases such as rheumatoid arthritis and lymphoma. It targets and inhibits Bruton’s tyrosine kinase (BTK), a critical enzyme in the activation of pro-inflammatory cells, thereby reducing inflammation and mitigating disease symptoms.
Used in Clinical Research:
PCI 29732 is used as a subject of clinical trials to further evaluate its therapeutic potential in treating inflammatory diseases. The ongoing trials aim to assess the safety, efficacy, and optimal dosing of the compound in patients with conditions like rheumatoid arthritis and lymphoma.

Upstream product

• 330786-24-8 3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 
• 96-41-3 Cyclopentanol