3308-99-4

Usage

Molecular Structure

The compound has a complex structure containing an isoindole ring and a dioxolane ring.

Isoindole ring

A bicyclic aromatic compound consisting of a six-membered benzene ring fused to a five-membered ring.

Dioxolane ring

A five-membered ring with two oxygen atoms as substituents.

Derivative of Isoindole-1,3(2H)-dione

The chemical name suggests that it is derived from isoindole-1,3(2H)-dione.

Isoindole-1,3(2H)-dione

A bicyclic compound with a ketone group on the isoindole ring.

Side Chain

The compound has a side chain consisting of a 2-phenyl-1,3-dioxolan-2-yl group attached to the nitrogen atom on the isoindole ring.

2-Phenyl-1,3-dioxolan-2-yl group

A phenyl group (a six-membered benzene ring) attached to a 1,3-dioxolan-2-yl group (a five-membered ring with two oxygen atoms as substituents).

Potential Applications

The compound may have potential applications in various fields, including medicinal chemistry and material science.

Medicinal Chemistry

The compound could potentially be used as a pharmaceutical agent or as a building block for the synthesis of other bioactive molecules.

Material Science

The compound may have unique physical or chemical properties that could be utilized in the development of new materials or technologies.

Further Research

Further research is needed to fully understand the properties and potential uses of 1H-Isoindole-1,3(2H)-dione, 2-[3-(2-phenyl-1,3-dioxolan-2-yl)propyl]-. This may include studying its chemical reactivity, stability, and biological activity.

Upstream product

• 939-52-6 4-chloro-1-phenylbutan-1-one 

Downstream Products

• 73434-11-4 2-Hydroxy-2-phenylpyrrolidine 
• 3239-88-1 2-(3-aminopropyl)-2-phenyl-1,3-dioxolane 
• 73434-01-2 1-Neopentyl-2-phenylpyrrolidine 
• 1006-64-0 2-(phenyl)pyrrolidine 
• 700-91-4 2-phenyl-1-pyrroline 

Relevant academic research and scientific papers

Azetidines. 5. Reaction of 1,1,3,3-Tetramethyl- and 1-Benzyl-1,3,3-trimethylazetidinium Ions with Butyllithium and Phenyllithium. Deuterium Labeling as a Mechanistic Probe

The reactions of 1,1,3,3-tetramethylazetidinium iodide (1) and 1-benzyl-1,3,3-trimethylazetidinium bromide (7) with butyllithium and with phenyllithium were studied in ether.The products from the reaction of 1 with butyllithium were 1,3,3-trimethylpyrrolidine (2), 3,3-dimethyl-4-(methylamino)-1-butene (3), 1-(dimethylamino)-2,2-dimethylheptane (4), neopentylpyrrolidine (5), and 1-(dimethylamino)-2,2-dimethylcyclopropane (6).With phenyllithium, 1 gave 2 and 1-(dimethylamino)-2,2-dimethyl-3-phenylpropane (11).With butyllithium, 7 gave 2-phenyl-1,4,4-trimethylpyrrolidine (8), 1-benzyl-3,3-dimethylpyrrolidine (9), and 1-neopentyl-2-phenylpyrrolidine (10).The reaction of phenyllithium with 7 gave only 8 and 9.Mechanistic information was obtained by labeling 1 with deuterium in three different ways: N-methyl-d3, 2,2-d2, and N-methyl-d3-2,2-d2.A primary kinetic isotope effect of 9.4 was found for the formation of 2 from 1-N-methyl-d3.When 2 was formed from 1-2,2-d2, a secondary kinetic isotope effect of 1.17 was measured.The formation of 4 from 1-2,2-d2 was accompanied by a primary kinetic isotope effect of 4.7, suggesting a carbene intermediate.Ylide carbanions involving decomposition to a carbene carbanion in the formation of 3 and an azomethine ylide in the formation of 5 and 9 are probable intermediates.It is postulated that the azomethine ylides react with ethylene formed from the reaction of butyllithium with the solvent ether by means of a concerted (4 + 2) cycloaddition reaction.A primary kinetic isotope effect of 20 was found for the formation of pentylbenzene from dibenzyldimethylammonium bromide and butyllithium.