11(R)-HEDE, also known as 11(R)-Hydroxyeicosadienoic acid, is a bioactive lipid mediator derived from the metabolism of arachidonic acid through the cyclooxygenase (COX) pathway. It plays a crucial role in various physiological and pathological processes, including inflammation and cell signaling.
330800-88-9
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Basic information
- Product Name: 11(R)-HEDE
- Synonyms: 11(R)-HEDE;11R-HYDROXY-12E,14Z-EICOSADIENOIC ACID;HDMIRVFIVOGVIC-VOYJXKAKSA-N
- CAS NO:330800-88-9
- Molecular Formula: C20H36O3
- Molecular Weight: 324.5
- EINECS: N/A
- Product Categories: N/A
- Mol File: 330800-88-9.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 11(R)-HEDE(CAS DataBase Reference)
- NIST Chemistry Reference: 11(R)-HEDE(330800-88-9)
- EPA Substance Registry System: 11(R)-HEDE(330800-88-9)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 330800-88-9(Hazardous Substances Data)
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330800-88-9 Usage
Uses
Used in Pharmaceutical Industry:11(R)-HEDE is used as a biomarker for monitoring the activity of cyclooxygenase (COX) enzymes, which are key players in the production of prostaglandins and other eicosanoids. The measurement of 11(R)-HEDE levels can help in understanding the role of COX enzymes in various diseases and the effectiveness of anti-inflammatory drugs targeting these enzymes.
Used in Research and Diagnostic Applications:
11(R)-HEDE is used as a research tool for studying the mechanisms of COX enzyme activity and its regulation. It can also be employed in the development of diagnostic tests to assess the risk and progression of inflammatory diseases, as well as the response to anti-inflammatory treatments.
Used in Drug Development:
11(R)-HEDE can be utilized in the development of novel therapeutic agents targeting COX enzymes or other pathways involved in the production of bioactive lipid mediators. Understanding the role of 11(R)-HEDE in cellular processes can lead to the discovery of new drug targets and the design of more effective medications for treating inflammation-related disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 330800-88-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,0,8,0 and 0 respectively; the second part has 2 digits, 8 and 8 respectively.Calculate Digit Verification of CAS Registry Number 330800-88:
(8*3)+(7*3)+(6*0)+(5*8)+(4*0)+(3*0)+(2*8)+(1*8)=109
109 % 10 = 9
So 330800-88-9 is a valid CAS Registry Number.
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11(R)-HEDE
