330850-44-7

Upstream product

• 24415-66-5 7-Chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine 
• 150-13-0 4-amino-benzoic acid 
• 2503-56-2 5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol 

Downstream Products

• 1333220-92-0 C₁₉H₁₅ClN₆O 
• 1333220-93-1 C₂₀H₁₈N₆O₂ 
• 1333220-94-2 C₂₀H₁₈N₆O₂ 
• 1333220-95-3 C₂₁H₂₀N₆O₃ 
• 900325-23-7 C₂₀H₁₈N₆O 
• 1333220-96-4 C₂₀H₁₈N₆O 
• 1333220-97-5 C₂₀H₁₈N₆O 
• 1333220-99-7 C₂₀H₁₈N₆O 

Relevant academic research and scientific papers

Synthesis, antibacterial and insecticidal activities of a new series of 4-(5-methyl-[1,2,4] triazolo [1,5-a] pyrimidin-7-ylamino)-N-(aryl) benzamides

A nevi/ series of 4-(5-methyl-[1,2,4] triazoio [1,5-a] pyrimidin-7-ylamino) -N-(aryl) benzamides (4a-i) were synthesized by coupling 4-(5-methyl-(1,2,4] triazoio [1,5-a] pyrimidin-7-ylamino) benzoic acid 3 with different substituted amines using O-(7-azabenzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate (HATU) as coupling reagent. The key intermediate 4-(5-methyl-[1,2,4] triazoio [1,5-a] pyrimidin-7-ylamino) benzoic acid 3 was synthesized by the reaction of 7-chloro-5-methyl-[1,2,4] triazoio [1,5-a] pyrimidine 2 with p-aminobenzoic acid in ethanol. The structure of the newly synthesized compounds were confirmed by FT-IR,1H NMR, 13C NMR and Mass spectral analysis and were evaluated for their antimicrobial and insecticidal activities. Some of the synthesized compounds exhibited potent insecticidal activity and significant antibacterial activity with respect to the standard drugs.