3309-57-7

Basic information

• Product Name: 2,5-Oxazolidinedione, 4-[(phenylmethoxy)methyl]-, (S)-
• CAS NO: 3309-57-7
• Molecular Formula: C11H11NO4
• Molecular Weight: 221.213
• Mol File: 3309-57-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,5-Oxazolidinedione, 4-[(phenylmethoxy)methyl]-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Oxazolidinedione, 4-[(phenylmethoxy)methyl]-, (S)-(3309-57-7)
• EPA Substance Registry System: 2,5-Oxazolidinedione, 4-[(phenylmethoxy)methyl]-, (S)-(3309-57-7)

Safety Data

• Hazardous Substances Data: 3309-57-7(Hazardous Substances Data)

Usage

General Description

"2,5-Oxazolidinedione, 4-[(phenylmethoxy)methyl]-, (S)-" is a specific chemical compound. It is an oxazolidinedione derivative, which refers to a class of organic compounds with a five-membered ring structure containing two oxygen atoms and one nitrogen atom. This particular compound also possesses a phenylmethoxy methyl group. The (S)- in its name implies that it has a specific chirality or spatial arrangement of atoms, in this case following the Cahn-Ingold-Prelog priority rules. Detailed information about its synthesis, properties, reactions, and use may vary and are typically documented in specific scientific or industrial contexts. The exact uses of this chemical are not specified but such chemicals are typically involved in various industrial applications and scientific research.

Upstream product

• 23680-31-1 BOC-O-benzyl-L-serine 
• 32315-10-9 bis(trichloromethyl) carbonate 

Downstream Products

• 125814-31-5 (S)-4-Benzyloxymethyl-2,5-dioxo-oxazolidine-3-carboxylic acid tert-butyl ester 

Relevant articles and documents

Synthesis of α-Amino Acid N-Carboxyanhydrides

A simple phosgene- and halogen-free method for synthesizing α-amino acid N-carboxyanhydrides (NCAs) is described. The reaction between Boc-protected α-amino acids and T3P reagent gave the corresponding NCA derivatives in good yield and purity with no detectable epimerization. The process is safe, is easy-to-operate, and does not require any specific installation. It generates nontoxic, easy to remove byproducts. It can apply to the preparation of NCAs for the on-demand on-site production of either little or large quantities.

Rapid and Mild Synthesis of Amino Acid N-Carboxy Anhydrides: Basic-to-Acidic Flash Switching in a Microflow Reactor

Polymerization of N-carboxy anhydrides (NCAs) is the primary process used to prepare polypeptides. The synthesis of various pure NCAs is key to the efficient synthesis of polypeptides. The only practical method that can be used to synthesize NCAs requires harsh acidic conditions that make acid-labile substrates unusable and results in an undesired ring opening of NCAs. Basic-to-acidic flash switching and subsequent flash dilution technology in a microflow reactor was used to demonstrate the synthesis of NCAs. It is both rapid (0.1 s) and mild (20 °C) and includes substrates containing acid-labile functional groups. The basic-to-acidic flash switching enabled both an acceleration of the desired NCA formation and avoided the undesired ring opening of NCAs. The flash dilution precluded the undesired decomposition of acid-labile functional groups. The developed process allowed the synthesis of various NCAs which cannot be readily synthesized using conventional batch methods.