33092-22-7

Basic information

• Product Name: 2-(4-benzoylphenyl)-2-phenylpropanenitrile
• CAS NO: 33092-22-7
• Molecular Weight: 311.383
• Mol File: 33092-22-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-benzoylphenyl)-2-phenylpropanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-benzoylphenyl)-2-phenylpropanenitrile(33092-22-7)
• EPA Substance Registry System: 2-(4-benzoylphenyl)-2-phenylpropanenitrile(33092-22-7)

Safety Data

• Hazardous Substances Data: 33092-22-7(Hazardous Substances Data)

Upstream product

• 1144-74-7 4-nitrobenzophenone 
• 1823-91-2 1-phenylethyl cyanide 
• 611-94-9 4-Methoxybenzophenone 

Relevant articles and documents

Catalytic C(sp2)-C(sp3) bond formation of methoxyarenes by the organic superbase t-Bu-P4

The organic superbase catalyst t-Bu-P4 achieves nucleophilic aromatic substitution of methoxyarenes with alkanenitrile pronucleophiles. A variety of functional groups [cyano, nitro, (non)enolizable ketone, chloride, and amide moieties] are allowed on methoxyarenes. Moreover, an array of alkanenitriles with/without an aryl moiety at the nitrile α-position can be employed. The system also features no requirement of a stoichiometric base, MeOH (not salt waste) formation as a byproduct, and the production of congested quaternary carbon centers.