330997-09-6 Usage
Description
N-(3-aminophenyl)-4-tert-butylbenzamide, a benzamide derivative with the molecular formula C16H20N2O, is a chemical compound that serves as an intermediate in the synthesis of various pharmaceutical compounds. It is recognized for its role as a reagent in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals. N-(3-AMINOPHENYL)-4-TERT-BUTYLBENZAMIDE is also utilized in research and analytical chemistry to study the properties and behavior of organic compounds. Its structural features and functional groups offer potential applications in drug discovery and development, allowing for modifications to achieve specific biological activity.
Uses
Used in Pharmaceutical Synthesis:
N-(3-aminophenyl)-4-tert-butylbenzamide is used as an intermediate in the synthesis of pharmaceutical compounds, contributing to the development of new medications.
Used in Organic Synthesis:
As a reagent in organic synthesis, N-(3-aminophenyl)-4-tert-butylbenzamide is employed in the preparation of pharmaceuticals and agrochemicals, facilitating the creation of a variety of chemical products.
Used in Research and Analytical Chemistry:
In research and analytical chemistry, N-(3-aminophenyl)-4-tert-butylbenzamide serves as a tool for studying the properties and behavior of organic compounds, aiding in the understanding and advancement of chemical knowledge.
Used in Drug Discovery and Development:
Due to its structural features and functional groups, N-(3-aminophenyl)-4-tert-butylbenzamide has potential applications in drug discovery and development. Its modifiable nature allows for the tailoring of specific biological activity, making it a valuable component in the creation of targeted therapeutics.
Check Digit Verification of cas no
The CAS Registry Mumber 330997-09-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,0,9,9 and 7 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 330997-09:
(8*3)+(7*3)+(6*0)+(5*9)+(4*9)+(3*7)+(2*0)+(1*9)=156
156 % 10 = 6
So 330997-09-6 is a valid CAS Registry Number.
330997-09-6Relevant articles and documents
Potent and selective inhibitors of the TASK-1 potassium channel through chemical optimization of a bis-amide scaffold
Flaherty, Daniel P.,Simpson, Denise S.,Miller, Melissa,Maki, Brooks E.,Zou, Beiyan,Shi, Jie,Wu, Meng,McManus, Owen B.,Aubé, Jeffrey,Li, Min,Golden, Jennifer E.
, p. 3968 - 3973 (2014/09/03)
TASK-1 is a two-pore domain potassium channel that is important to modulating cell excitability, most notably in the context of neuronal pathways. In order to leverage TASK-1 for therapeutic benefit, its physiological role needs better characterization; however, designing selective inhibitors that avoid the closely related TASK-3 channel has been challenging. In this study, a series of bis-amide derived compounds were found to demonstrate improved TASK-1 selectivity over TASK-3 compared to reported inhibitors. Optimization of a marginally selective hit led to analog 35 which displays a TASK-1 IC 50 = 16 nM with 62-fold selectivity over TASK-3 in an orthogonal electrophysiology assay.
