33100-53-7

Usage

Uses

Used in Pharmaceutical Industry:
(1H-benzo[d]imidazol-2-yl)(phenyl)methanamine is used as a chemical intermediate for the development of pharmaceuticals due to its potential pharmacological properties. Its unique structure allows it to be a target for drug development and research, potentially leading to the creation of new medications.
Used in Organic Synthesis:
In the field of organic synthesis, (1H-benzo[d]imidazol-2-yl)(phenyl)methanamine serves as a key building block for synthesizing more complex organic compounds. Its aromatic properties and molecular structure make it a valuable component in the creation of advanced organic molecules.
Used in Material Science:
(1H-benzo[d]imidazol-2-yl)(phenyl)methanamine is utilized in material science for the development of new materials with specific properties. Its unique structure and aromatic nature contribute to the design and synthesis of novel materials with potential applications in various industries.

Upstream product

• 95-54-5 1,2-diamino-benzene 
• 2835-06-5 phenylglycin 
• 2900-27-8 2-(tert-butoxycarbonylamino)-2-phenylacetic acid 
• 17599-61-0 N-benzylidene-1,1,1-trimethylsilanamine 
• 18249-98-4 1-(methoxymethyl)-1H-benzo[d]imidazole 
• 102479-69-6 N-[(1H-benzimidazol-2-yl)-phenyl-methyl]-toluene-4-sulfonamide 

Downstream Products

• 105485-40-3 4-{[(1H-Benzoimidazol-2-yl)-phenyl-methyl]-amino}-1,5-diphenyl-1,5-dihydro-pyrrol-2-one 
• 1053635-49-6 {(S)-1-[(S)-1-((1S,2S)-4-{[(1H-Benzoimidazol-2-yl)-phenyl-methyl]-carbamoyl}-1-benzyl-2-hydroxy-butylcarbamoyl)-ethylcarbamoyl]-ethyl}-carbamic acid tert-butyl ester 
• 1252600-20-6 C₁₇H₂₀N₄ 

Relevant academic research and scientific papers

Discovery of small molecule human FPR1 receptor antagonists

The identification of two novel series of formyl peptide receptor 1 (FPR1) antagonists are reported, represented by methionine benzimidazole 6 and diamide 7. Both series specifically inhibited the binding of labelled fMLF to hrFPR1 and selectively antagonized FPR1 function in human neutrophils, making them useful in vitro validation tools for the target.

Synthesis, characterization and biological evaluation of 1, 2-disubstituted benzimidazole derivatives using Mannich bases

The ring system in which a benzene ring is fused to the 4,5-positions of imidazole is designated as benzimidazole. Condensations of 2-substituted benzimidazole derivatives were synthesized by different carboxylic acids using Mannich base and anti-inflammatory activity. The various positions on the benzimidazole ring are numbered in the manner indicated with the imino function as number one. The formations of the product were conformed by the analytical and spectral data.

Crystal-structure-based design and synthesis of novel C-terminal inhibitors of HIV protease

The X-ray crystal-structure-based design, synthesis, computational evaluation, and activity of a novel class of HIV protease inhibitors are described. The initial lead compounds 2 and 3 were designed by modeling replacement groups for the C-terminal Val-V