33119-75-4

Upstream product

• 31366-07-1 3,3-dimethyl-1-phenyl-butan-1-one 
• 71129-94-7 C₁₄H₂₀LiN 
• 4604-28-8 (Z)-β-chlorostyrene 
• 71129-92-5 chloro-2 dimethylamino-1 phenyl-1 ethylene 
• 7065-46-5 3,3-dimethylbutanoic acid chloride 
• 71-43-2 benzene 
• 3846-66-0 (E)-1-tert-butyl-2-phenylethene 

Downstream Products

• 31366-07-1 3,3-dimethyl-1-phenyl-butan-1-one 
• 108511-32-6 2-(Hydroxy-phenyl-methyl)-3,3-dimethyl-1-phenyl-butan-1-one 
• 108511-32-6 2-(Hydroxy-phenyl-methyl)-3,3-dimethyl-1-phenyl-butan-1-one 
• 77387-76-9 3,3-Dimethyl-1-phenyl-1-thioxo-2-butanon 
• 77387-78-1 3,3-Dimethyl-1-phenyl-2-thioxo-1-butanon 

Relevant academic research and scientific papers

Generation of Dimethyl Sulfoxide Coordinated Thermally Stable Halogen Cation Pools for C?H Halogenation

A method to generate halogen cation pools from the reaction of 1,2-dihaloethanes (hal=Br, I) and dimethyl sulfoxide (DMSO) for C?H halogenation of arenes and heteroarenes was reported. The initial reaction of DMSO and 1,2-dihaloethane generates the sulfur

Enamines β-lithiees. I. Preparations et reactions d'alkylation

The action of alkyllithium reagents on β-bromoenamines 1-9 quickly yields, in THF, β-lithioenamines through halogen - metal exchange.If metallic lithium is used instead of organolithium compounds, β-lithioenamines are also formed but in this case they are accompanied by small amounts of by-products.The action of alkyllithium reagents R1Li on the β-chloroenamine 10 provides a new source of β-lithioenamines in which nucleophilic insertion of the R1 group takes place. β-Lithioenamines are stable compounds even up to 20 deg C in most cases.With alkyl iodides, β-lithioenamines react vigorously even at low temperature.The reaction is stereospecific with retention of configuration.This reaction generates either β-substituted enamines or, by easy acidic hydrolysis, α-substituted carbonyl compounds.The C-alkylation reaction is observed alone.

Preparation of Diaryl and Aryl tert-Butyl α-Thioxoketones

The preparation of the α-haloketones 6, 13-16, 19, and 20 is reported. 13 or its precursor, the acyloin 9, respectively, is conveniently obtained by a Seebach synthesis. - Reaction of the haloketones with tetraethylammonium thiosulfate (21) yields the Bunte salts 22-27 wich form the thioketones 28-33 on cleavage with aqueous alkali. 29 is stable as a crystalline, blue monomer in contrast with other aromatic α-thioxoketones.This ist also true for the aromatic-aliphatic derivatives 30 and 31 as well as their isomers 32 and 33 wich do not dimerize.