33123-73-8 Usage
Uses
Used in Pharmaceutical Synthesis:
4,5-DiMethyl-2-Oxazolecarboxylic Acid Ethyl Ester is used as a key intermediate in the synthesis of pharmaceutical compounds. Its unique chemical structure allows for the creation of a wide range of biologically active molecules with potential applications in various therapeutic areas.
Used in Factor Xa Inhibitors Preparation:
In the field of anticoagulant drug development, 4,5-DiMethyl-2-Oxazolecarboxylic Acid Ethyl Ester is used as an intermediate in the preparation of novel factor Xa inhibitors. Factor Xa is a crucial enzyme in the coagulation cascade, and its inhibition can help prevent blood clot formation, making it a target for the treatment of conditions such as deep vein thrombosis, pulmonary embolism, and stroke.
Used in Medicinal Chemistry Research:
4,5-DiMethyl-2-Oxazolecarboxylic Acid Ethyl Ester is also utilized in medicinal chemistry research for the design and synthesis of new drug candidates. Its versatile chemical structure allows for the exploration of various structural modifications and the evaluation of their impact on biological activity, potentially leading to the discovery of more effective and selective therapeutic agents.
Used in Drug Delivery Systems:
In the development of drug delivery systems, 4,5-DiMethyl-2-Oxazolecarboxylic Acid Ethyl Ester can be employed as a component in the design of novel carriers for targeted drug delivery. Its chemical properties may enable the creation of systems that can improve the bioavailability, stability, and targeted delivery of therapeutic agents, ultimately enhancing their efficacy and safety.
Check Digit Verification of cas no
The CAS Registry Mumber 33123-73-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,1,2 and 3 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 33123-73:
(7*3)+(6*3)+(5*1)+(4*2)+(3*3)+(2*7)+(1*3)=78
78 % 10 = 8
So 33123-73-8 is a valid CAS Registry Number.
33123-73-8Relevant academic research and scientific papers
Oxazoles from β-acyloxy-N,N-bis(trimethylsilyl)enamines
Cunico,Kuan
, p. 1945 - 1948 (2007/10/02)
Sequential addition of methyllithium and acyl chlorides to O-trimethylsilyl acetyltrimethylsilane cyanohydrin affords β-acyloxy-N,N-bis(trimethylsilyl)enamines which cyclize to 2-substituted-4,5-dimethyloxazoles under thermolysis or trimethylsilyl trifluoromethanesulfonate treatment.
REACTIONS OF OXAZOLES WITH ACETYLENE DERIVATIVES. PART III. REACTIONS OF TRISUBSTITUTED OXAZOLE DERIVATIVES WITH ETHYL PROPIOLATE
Jaworski, Tadeusz,Mizerski, Tadeusz
, p. 47 - 56 (2007/10/02)
Diene reactions between dimethyloxazoles containing an electron accepting group in positions 2 or 5 with ethyl propiolate were investigated.The formation of both possible, isomeric furan derivatives was stated in the case of all these reactions.The ratio of both products depends on the kind of the electron accepting group and does not depend on the places of methyl and electron accepting groups in positions 2 and 5 in the oxazole.
