33124-04-8Relevant academic research and scientific papers
NOVEL IMIDAZOTHIAZOLES AND IMIDAZOXAZOLES
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Page/Page column 51, (2008/12/05)
The present invention is directed to novel compounds of formula (I) wherein the variables are as defined herein. The compounds of formula (I) are useful as kinase inhibitors and as such would be useful in treating certain conditions and diseases, especially inflammatory conditions and diseases and proliferative disorders and conditions, for example, cancers.
Gas-Phase Thermal Isomerization of Some Aminomethylisoxazoles
Perez, Jorge D.,Diaz, Rosario G. de,Yranzo, Gloria I.
, p. 3505 - 3508 (2007/10/02)
The kinetic results from the gas-phase thermal isomerization of 5-amino-3,4-dimethylisoxazole (1), 3,5-dimethylisoxazole (2), and 3-amino-5-methylisoxazole (3) are reported.Compound 1 afforded quantitatively 3-carbamoyl-2,3-dimethyl-1-azirine (4).On the other hand, 2 and 3 gave the isomeric oxazoles 5 and 7, respectively.Different reaction pathways are discussed according to the activation parameters.
