331436-06-7Relevant academic research and scientific papers
Discovery of antiglioma activity of biaryl 1,2,3,4-tetrahydroisoquinoline derivatives and conformationally flexible analogues
Mohler, Michael L.,Kang, Gyong-Suk,Hong, Seoung-Soo,Patil, Renukadevi,Kirichenko, Oleg V.,Li, Wei,Rakov, Igor M.,Geisert, Eldon E.,Miller, Duane D.
, p. 5845 - 5848 (2006)
Cultured rat astrocytes and C6 rat glioma were used as a differential screen for a variety of 1,2,3,4-tetrahydroisoquinoline (THI) derivatives. Compound 1[1-(biphenyl-4-ylmethyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrochloride] selectively blocked t
