331625-82-2

Upstream product

• 331626-41-6 (3S,4R,5R)-2-Allyloxy-3,4-bis-(4-methoxy-benzyloxy)-5-(4-methoxy-benzyloxymethyl)-tetrahydro-furan 
• 773896-71-2 allyl arabinofuranoside 
• 532-20-7 D-arabinofuranose 
• 76-83-5 trityl chloride 
• 331626-43-8 (2R,3R,4R)-2,3,5-Tris-(4-methoxy-benzyloxy)-pentane-1,4-diol 

Downstream Products

• 331625-83-3 (2S,3R,4R)-1,3,4-tris(4-methoxybenzyloxy)-5-(trityloxy)-2-pentanol 
• 637741-53-8 [(2R,3R,4R)-4-Azido-2,3,5-tris-(4-methoxy-benzyloxy)-pentyloxy]-tert-butyl-dimethyl-silane 
• 637740-95-5 (2R,3R,4R)-1,3,4-tris(4-methoxybenzyloxy)-5-(tert-butyldimethylsiloxy)pentane-2-amine 
• 637740-96-6 (2R,3R,4R)-N-(2,4-dimethoxybenzyl)-1,3,4-tris(4-methoxybenzyloxy)-5-(tert-butyl-dimethylsiloxy)pentane-2-amine 
• 331626-36-9 (E)-2-Methyl-pentadec-2-enoic acid (1R,2R,3S)-2,3-bis-(4-methoxy-benzyloxy)-1-(4-methoxy-benzyloxymethyl)-3-methoxycarbonyl-propyl ester 
• 331626-33-6 (E)-2-Methyl-pentadec-2-enoic acid (1R,2S,3R)-4-hydroxy-2,3-bis-(4-methoxy-benzyloxy)-1-(4-methoxy-benzyloxymethyl)-butyl ester 

Relevant academic research and scientific papers

Chemistry and biology of khafrefungin. Large-scale synthesis, design, and structure-activity relationship of khafrefungin, an antifungal agent

Large-scale synthesis, design, and structure-activity relationships of khafrefungin are reported. Khafrefungin is an antifungal agent that inhibits inositol phosphorylceramide (IPC) synthase, a enzyme involved in fungal sphingolipid biosynthesis. Unlike o

Total synthesis and structural elucidation of khafrefungin

Total synthesis and structural elucidation of khafrefungin, a novel antifungal agent isolated from the fermentation culture MF6020, have been achieved. Unlike other inhibitors that inhibit the corresponding enzyme in fungi and mammals to the same extent,