331626-05-2Relevant academic research and scientific papers
Total synthesis of khafrefungin using highly stereoselective vinylogous Mukaiyama aldol reaction
Shirokawa, Shin-Ichi,Shinoyama, Mariko,Ooi, Isao,Hosokawa, Seijiro,Nakazaki, Atsuo,Kobayashi, Susumu
, p. 849 - 852 (2007/10/03)
(Chemical Equation Presented) A convergent total synthesis of khafrefungin was accomplished on the basis of (1) the highly stereoselective TiCl 4-mediated vinylogous Mukaiyama aldol reaction using vinylketene silyl N,O-acetal and (2) syn-select
Total synthesis and structural elucidation of khafrefungin
Wakabayashi,Mori,Kobayashi
, p. 1372 - 1375 (2007/10/03)
Total synthesis and structural elucidation of khafrefungin, a novel antifungal agent isolated from the fermentation culture MF6020, have been achieved. Unlike other inhibitors that inhibit the corresponding enzyme in fungi and mammals to the same extent,
