331683-65-9Relevant academic research and scientific papers
A new class of nonsteroidal aromatase inhibitors: Design and synthesis of chromone and xanthone derivatives and inhibition of the P450 enzymes aromatase and 17α-hydroxylase/C17,20-lyase
Recanatini,Hartmann,Bisi,Cavalli,Belluti,Gobbi,Rampa,Valenti,Palzer,Palusczak
, p. 672 - 680 (2007/10/03)
Aromatase (P450arom) is a target of pharmacological interest for the treatment of breast cancer. In this paper, we report the design, synthesis, and in vitro biological evaluation of a series of new (di)benzopyranone-based inhibitors of this enzyme. The d
