Basic information

Product Name: (R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide Dihydrochloride Monohydrate
Synonyms: (R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide Dihydrochloride Monohydrate;trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinyl-cyclohexanecarboxamide Dihydrochloride Monohydrate;Cyclohexanecarboxamide, 4-[(1R)-1-aminoethyl]-N-4-pyridinyl-, dihydrochloride, monohydrate, trans- (9CI);(R)-(+)-trans-4-(1-Aminoethyl)-N-(4-Pyridyl)cyclohexanecarboxamide monohydrate dihydrochloride;Y-27632 monohydrate dihydrochloride;Y-27632 Dihydrochloride Hydrate;Y-27632 dihydrochloride monohydrate;Y-27632 2HCl Monohydrate
CAS NO:331752-47-7
Molecular Formula: C14H25Cl2N3O2
Molecular Weight: 0
EINECS: N/A
Product Categories: All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Protein Kinase Inhibitors and Activators;Pfizer Compounds
Mol File: 331752-47-7.mol

Chemical Properties

Melting Point: 180-230°C
Boiling Point: approximate 85℃
Flash Point: N/A
Appearance: /
Density: N/A
Refractive Index: N/A
Storage Temp.: 2-8°C
Solubility: Acetonitrile (Very Slightly), DMSO (Slightly), Methanol (Slightly), Water (Sligh
Stability: Hygroscopic; Light Sensitive;
CAS DataBase Reference: (R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide Dihydrochloride Monohydrate(CAS DataBase Reference)
NIST Chemistry Reference: (R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide Dihydrochloride Monohydrate(331752-47-7)
EPA Substance Registry System: (R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide Dihydrochloride Monohydrate(331752-47-7)

Safety Data

Hazard Codes: Xn
Statements: 20/21/22
Safety Statements: 36
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 331752-47-7(Hazardous Substances Data)

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331752-47-7 Usage

Uses

Used in Pharmaceutical Industry:
(R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide Dihydrochloride Monohydrate is used as a Rho kinase inhibitor (ROCK) for the treatment of ischemia-reperfusion disorders. Its potent ROCK inhibitory activity makes it a promising candidate for the development of therapeutic agents targeting conditions associated with ischemia and reperfusion injury.
Used in Medical Research:
In the field of medical research, (R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide Dihydrochloride Monohydrate is utilized as a valuable tool for studying the role of ROCK in various cellular processes and disease mechanisms. Its ability to inhibit ROCK can provide insights into the development of new therapeutic strategies for treating ischemia-reperfusion disorders and other related conditions.
Chemical Properties:
(R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide Dihydrochloride Monohydrate is a white solid, which indicates its stability and suitability for use in various pharmaceutical formulations and experimental setups. Its chemical properties, including its potent ROCK inhibitory activity, make it a valuable asset in the development of new drugs and therapies for a range of medical conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 331752-47-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,1,7,5 and 2 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 331752-47:
(8*3)+(7*3)+(6*1)+(5*7)+(4*5)+(3*2)+(2*4)+(1*7)=127
127 % 10 = 7
So 331752-47-7 is a valid CAS Registry Number.

331752-47-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name	(R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide Dihydrochloride Monohydrate

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:331752-47-7 SDS

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